Titre
The multifaceted adult epidermal stem cell
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Gambardella, L.
Auteure/Auteur
Barrandon, Y.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0955-0674
Statut éditorial
Publié
Date de publication
2003-12
Volume
15
Numéro
6
Première page
771
Dernière page/numéro d’article
7
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Dec
Research Support, Non-U.S. Gov't
Review --- Old month value: Dec
Résumé
Adult epidermal stem cells renew the epithelial compartment of the skin throughout life and are the most accessible of all adult stem cells. Most importantly, epidermal stem cells can be efficiently cultivated and transplanted, a significant advantage for cell and gene therapy. Recent work has pointed to the hair follicle as the main repository of multipotent stem cells in skin. Hair follicles, which are often affected in the mouse by spontaneous or man-made mutations, have become superb model systems to study the cellular and molecular factors that regulate the proliferation, migration and fate of adult stem cells.
Sujets
PID Serval
serval:BIB_870EEF888039
PMID
Date de création
2008-01-28T07:41:59.053Z
Date de création dans IRIS
2025-05-20T22:29:38Z