Titre
Effect of short-term creatine supplementation on renal responses in men.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Poortmans, J.R.
Auteure/Auteur
Auquier, H.
Auteure/Auteur
Renaut, V.
Auteure/Auteur
Durussel, A.
Auteure/Auteur
Saugy, M.
Auteure/Auteur
Brisson, G.R.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0301-5548
Statut éditorial
Publié
Date de publication
1997
Volume
76
Numéro
6
Première page
566
Dernière page/numéro d’article
567
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Clinical Trial ; Controlled Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Résumé
There is an increasing utilisation of oral creatine (Cr) supplementation among athletes who hope to enhance their performance but it is not known if this ingestion has any detrimental effect on the kidney. Five healthy men ingested either a placebo or 20 g of creatine monohydrate per day for 5 consecutive days. Blood samples and urine collections were analysed for Cr and creatinine (Crn) determination after each experimental session. Total protein and albumin urine excretion rates were also determined. Oral Cr supplementation had a significant incremental impact on arterial content (3.7 fold) and urine excretion rate (90 fold) of this compound. In contrast, arterial and urine Crn values were not affected by the Cr ingestion. The glomerular filtration rate (Crn clearance) and the total protein and albumin excretion rates remained within the normal range. In conclusion, this investigation showed that short-term oral Cr supplementation does not appear to have any detrimental effect on the renal responses of healthy men.
PID Serval
serval:BIB_E591BC945DD5
PMID
Date de création
2009-03-28T11:46:26.228Z
Date de création dans IRIS
2025-05-21T01:00:42Z