Titre
A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Mack Wendy, J.
Auteure/Auteur
Preston-Martin, Susan
Auteure/Auteur
Dal Maso, Luigino
Auteure/Auteur
Galanti, Rosaria
Auteure/Auteur
Xiang, Min
Auteure/Auteur
Franceschi, Silvia
Auteure/Auteur
Hallquist, Arne
Auteure/Auteur
Jin, Fan
Auteure/Auteur
Kolonel, Laurence
Auteure/Auteur
La Vecchia, Carlo
Auteure/Auteur
Levi, Fabio
Auteure/Auteur
Linos, Athena
Auteure/Auteur
Lund, Eiliv
Auteure/Auteur
McTiernan, Anne
Auteure/Auteur
Mabuchi, Kiyohiko
Auteure/Auteur
Negri, Eva
Auteure/Auteur
Wingren, Gun
Auteure/Auteur
Ron, Elaine
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0957-5243
Statut éditorial
Publié
Date de publication
2003
Volume
14
Numéro
8
Première page
773
Dernière page/numéro d’article
785
Notes
Réf.: R 03/119 SAPHIRID:44923
Résumé
[Abstract] OBJECTIVE: To analyze the role of smoking, alcohol, coffee and tea in relation to thyroid cancer, we conducted a pooled analysis of 14 case-control studies conducted in the United States, Europe, and Asia. METHODS: The sample consisted of 2725 thyroid cancer cases (2247 females, 478 males) and 4776 controls (3699 females, 1077 males). Conditional logistic regression with stratification on study, age at diagnosis, and gender was used to compute odds ratios and 95% confidence intervals. RESULTS: Thyroid cancer risk was reduced in persons who had ever smoked. The relationship was more pronounced in current smokers (OR = 0.6, 95% CI = 0.6-0.7) than former smokers (OR = 0.9, 95% CI = 0.8-1.1). There were significant trends of reduced risk with greater duration and frequency of smoking. For consumption of wine and beer, there was a significant trend of decreasing thyroid cancer risk (p = 0.02) that was not maintained after adjustment for current smoking (p = 0.12). Thyroid cancer risk was not associated with consumption of coffee or tea. These findings were consistent in both gender-specific and histology-specific (papillary and follicular) analyses. CONCLUSIONS: Pooled analyses of these geographically diverse case-control data indicate a reduced thyroid cancer risk associated with current smoking. A reduced risk associated with alcohol was eliminated after adjustment for smoking, and caffeinated beverages did not alter thyroid cancer risk. [Authors]
PID Serval
serval:BIB_2807EAC3603F
PMID
Date de création
2008-03-06T14:31:29.068Z
Date de création dans IRIS
2025-05-20T13:21:22Z