Titre
Global survival trends for brain tumors, by histology: analysis of individual records for 556,237 adults diagnosed in 59 countries during 2000-2014 (CONCORD-3).
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Girardi, F.
Auteure/Auteur
Matz, M.
Auteure/Auteur
Stiller, C.
Auteure/Auteur
You, H.
Auteure/Auteur
Marcos Gragera, R.
Auteure/Auteur
Valkov, M.Y.
Auteure/Auteur
Bulliard, J.L.
Auteure/Auteur
De, P.
Auteure/Auteur
Morrison, D.
Auteure/Auteur
Wanner, M.
Auteure/Auteur
O'Brian, D.K.
Auteure/Auteur
Saint-Jacques, N.
Auteure/Auteur
Coleman, M.P.
Auteure/Auteur
Allemani, C.
Auteure/Auteur
Contributrices/contributeurs
Bouzbid, S.
Hamdi-Chérif, M.
Kara, L.
Meguenni, K.
Regagba, D.
Bayo, S.
Cheick Bougadari, T.
Manraj, S.S.
Bendahhou, K.
Ladipo, A.
Ogunbiyi, O.J.
Somdyala, NIM
Chaplin, M.A.
Moreno, F.
Calabrano, G.H.
Espinola, S.B.
Carballo Quintero, B.
Fita, R.
Laspada, W.D.
Ibañez, S.G.
Lima, C.A.
Da Costa, A.M.
De Souza, PCF
Chaves, J.
Laporte, C.A.
Curado, M.P.
de Oliveira, J.C.
Veneziano, CLA
Veneziano, D.B.
Almeida, ABM
Latorre, MRDO
Rebelo, M.S.
Santos, M.O.
Azevedo E Silva, G.
Galaz, J.C.
Aparicio Aravena, M.
Sanhueza Monsalve, J.
Herrmann, D.A.
Vargas, S.
Herrera, V.M.
Uribe, C.J.
Bravo, L.E.
Garcia, L.S.
Arias-Ortiz, N.E.
Morantes, D.
Jurado, D.M.
Yépez Chamorro, M.C.
Delgado, S.
Ramirez, M.
Galán Alvarez, Y.H.
Torres, P.
Martínez-Reyes, F.
Jaramillo, L.
Quinto, R.
Castillo, J.
Mendoza, M.
Cueva, P.
Yépez, J.G.
Bhakkan, B.
Deloumeaux, J.
Joachim, C.
Macni, J.
Carrillo, R.
Shalkow Klincovstein, J.
Rivera Gomez, R.
Perez, P.
Poquioma, E.
Tortolero-Luna, G.
Zavala, D.
Alonso, R.
Barrios, E.
Eckstrand, A.
Nikiforuk, C.
Woods, R.R.
Noonan, G.
Turner, D.
Kumar, E.
Zhang, B.
Dowden, J.J.
Doyle, G.P.
Saint-Jacques, N.
Walsh, G.
Anam, A.
De, P.
McClure, C.A.
Vriends, K.A.
Bertrand, C.
Ramanakumar, A.V.
Davis, L.
Kozie, S.
Freeman, T.
George, J.T.
Avila, R.M.
O'Brien, D.K.
Holt, A.
Almon, L.
Kwong, S.
Morris, C.
Rycroft, R.
Mueller, L.
Phillips, C.E.
Brown, H.
Cromartie, B.
Ruterbusch, J.
Schwartz, A.G.
Levin, G.M.
Wohler, B.
Bayakly, R.
Ward, K.C.
Gomez, S.L.
McKinley, M.
Cress, R.
Davis, J.
Hernandez, B.
Johnson, C.J.
Morawski, B.M.
Ruppert, L.P.
Bentler, S.
Charlton, M.E.
Huang, B.
Tucker, T.C.
Deapen, D.
Liu, L.
Hsieh, M.C.
Wu, X.C.
Schwenn, M.
Stern, K.
Gershman, S.T.
Knowlton, R.C.
Alverson, G.
Weaver, T.
Desai, J.
Rogers, D.B.
Jackson-Thompson, J.
Lemons, D.
Zimmerman, H.J.
Hood, M.
Roberts-Johnson, J.
Hammond, W.
Rees, J.R.
Pawlish, K.S.
Stroup, A.
Key, C.
Wiggins, C.
Kahn, A.R.
Schymura, M.J.
Radhakrishnan, S.
Rao, C.
Giljahn, L.K.
Slocumb, R.M.
Dabbs, C.
Espinoza, R.E.
Aird, K.G.
Beran, T.
Rubertone, J.J.
Slack, S.J.
Oh, J.
Janes, T.A.
Schwartz, S.M.
Chiodini, S.C.
Hurley, D.M.
Whiteside, M.A.
Rai, S.
Williams, M.A.
Herget, K.
Sweeney, C.
Kachajian, J.
Keitheri Cheteri, M.B.
Migliore Santiago, P.
Blankenship, S.E.
Conaway, J.L.
Borchers, R.
Malicki, R.
Espinoza, J.
Grandpre, J.
Weir, H.K.
Wilson, R.
Edwards, B.K.
Mariotto, A.
Rodriguez-Galindo, C.
Wang, N.
Yang, L.
Chen, J.S.
Zhou, Y.
He, Y.T.
Song, G.H.
Gu, X.P.
Mei, D.
Mu, H.J.
Ge, H.M.
Wu, T.H.
Li, Y.Y.
Zhao, D.L.
Jin, F.
Zhang, J.H.
Zhu, F.D.
Junhua, Q.
Yang, Y.L.
Jiang, C.X.
Biao, W.
Wang, J.
Li, Q.L.
Yi, H.
Zhou, X.
Dong, J.
Li, W.
Fu, F.X.
Liu, S.Z.
Chen, J.G.
Zhu, J.
Li, Y.H.
Lu, Y.Q.
Fan, M.
Huang, S.Q.
Guo, G.P.
Zhaolai, H.
Wei, K.
Chen, W.Q.
Wei, W.
Zeng, H.
Demetriou, A.V.
Mang, W.K.
Ngan, K.C.
Kataki, A.C.
Krishnatreya, M.
Jayalekshmi, P.A.
Sebastian, P.
George, P.S.
Mathew, A.
Nandakumar, A.
Malekzadeh, R.
Roshandel, G.
Keinan-Boker, L.
Silverman, B.G.
Ito, H.
Koyanagi, Y.
Sato, M.
Tobori, F.
Nakata, I.
Teramoto, N.
Hattori, M.
Kaizaki, Y.
Moki, F.
Sugiyama, H.
Utada, M.
Nishimura, M.
Yoshida, K.
Kurosawa, K.
Nemoto, Y.
Narimatsu, H.
Sakaguchi, M.
Kanemura, S.
Naito, M.
Narisawa, R.
Miyashiro, I.
Nakata, K.
Mori, D.
Yoshitake, M.
Oki, I.
Fukushima, N.
Shibata, A.
Iwasa, K.
Ono, C.
Matsuda, T.
Nimri, O.
Jung, K.W.
Won, Y.J.
Alawadhi, E.
Elbasmi, A.
Ab Manan, A.
Adam, F.
Nansalmaa, E.
Tudev, U.
Ochir, C.
Al Khater, A.M.
El Mistiri, M.M.
Lim, G.H.
Teo, Y.Y.
Chiang, C.J.
Lee, W.C.
Buasom, R.
Sangrajrang, S.
Suwanrungruang, K.
Vatanasapt, P.
Daoprasert, K.
Pongnikorn, D.
Leklob, A.
Sangkitipaiboon, S.
Geater, S.L.
Sriplung, H.
Ceylan, O.
Kög, I.
Dirican, O.
Köse, T.
Gurbuz, T.
Karaşahin, F.E.
Turhan, D.
Aktaş, U.
Halat, Y.
Eser, S.
Yakut, C.I.
Altinisik, M.
Cavusoglu, Y.
Türkköylü, A.
Üçüncü, N.
Hackl, M.
Zborovskaya, A.A.
Aleinikova, O.V.
Henau, K.
Van Eycken, L.
Atanasov, T.Y.
Valerianova, Z.
Šekerija, M.
Dušek, L.
Zvolský, M.
Steinrud Mørch, L.
Storm, H.
Wessel Skovlund, C.
Innos, K.
Mägi, M.
Malila, N.
Seppä, K.
Jégu, J.
Velten, M.
Cornet, E.
Troussard, X.
Bouvier, A.M.
Guizard, A.V.
Bouvier, V.
Launoy, G.
Dabakuyo Yonli, S.
Poillot, M.L.
Maynadié, M.
Mounier, M.
Vaconnet, L.
Woronoff, A.S.
Daoulas, M.
Robaszkiewicz, M.
Clavel, J.
Poulalhon, C.
Desandes, E.
Lacour, B.
Baldi, I.
Amadeo, B.
Coureau, G.
Monnereau, A.
Orazio, S.
Audoin, M.
D'Almeida, T.C.
Boyer, S.
Hammas, K.
Trétarre, B.
Colonna, M.
Delafosse, P.
Plouvier, S.
Cowppli-Bony, A.
Molinié, F.
Bara, S.
Ganry, O.
Lapôtre-Ledoux, B.
Daubisse-Marliac, L.
Bossard, N.
Uhry, Z.
Estève, J.
Stabenow, R.
Wilsdorf-Köhler, H.
Eberle, A.
Luttmann, S.
Löhden, I.
Nennecke, A.L.
Kieschke, J.
Sirri, E.
Justenhoven, C.
Reinwald, F.
Holleczek, B.
Eisemann, N.
Katalinic, A.
Asquez, R.A.
Kumar, V.
Petridou, E.
Ólafsdóttir, E.J.
Tryggvadóttir, L.
Murray, D.E.
Walsh, P.M.
Sundseth, H.
Harney, M.
Mazzoleni, G.
Vittadello, F.
Coviello, E.
Cuccaro, F.
Galasso, R.
Sampietro, G.
Giacomin, A.
Magoni, M.
Ardizzone, A.
D'Argenzio, A.
Di Prima, A.A.
Ippolito, A.
Lavecchia, A.M.
Sutera Sardo, A.
Gola, G.
Ballotari, P.
Giacomazzi, E.
Ferretti, S.
Dal Maso, L.
Serraino, D.
Celesia, M.V.
Filiberti, R.A.
Pannozzo, F.
Melcarne, A.
Quarta, F.
Andreano, A.
Russo, A.G.
Carrozzi, G.
Cirilli, C.
Cavalieri d'Oro, L.
Rognoni, M.
Fusco, M.
Vitale, M.F.
Usala, M.
Cusimano, R.
Mazzucco, W.
Michiara, M.
Sgargi, P.
Boschetti, L.
Marguati, S.
Chiaranda, G.
Seghini, P.
Maule, M.M.
Merletti, F.
Spata, E.
Tumino, R.
Mancuso, P.
Cassetti, T.
Sassatelli, R.
Falcini, F.
Giorgetti, S.
Caiazzo, A.L.
Cavallo, R.
Piras, D.
Bella, F.
Madeddu, A.
Fanetti, A.C.
Maspero, S.
Carone, S.
Mincuzzi, A.
Candela, G.
Scuderi, T.
Gentilini, M.A.
Rizzello, R.
Rosso, S.
Caldarella, A.
Intrieri, T.
Bianconi, F.
Contiero, P.
Tagliabue, G.
Rugge, M.
Zorzi, M.
Beggiato, S.
Brustolin, A.
Gatta, G.
De Angelis, R.
Vicentini, M.
Zanetti, R.
Stracci, F.
Maurina, A.
Oniščuka, M.
Mousavi, M.
Steponaviciene, L.
Vincerževskienė, I.
Azzopardi, M.J.
Calleja, N.
Siesling, S.
Visser, O.
Johannesen, T.B.
Larønningen, S.
Trojanowski, M.
Macek, P.
Mierzwa, T.
Rachtan, J.
Rosińska, A.
Kępska, K.
Kościańska, B.
Barna, K.
Sulkowska, U.
Gebauer, T.
Łapińska, J.B.
Wójcik-Tomaszewska, J.
Motnyk, M.
Patro, A.
Gos, A.
Sikorska, K.
Bielska-Lasota, M.
Didkowska, J.A.
Wojciechowska, U.
Forjaz de Lacerda, G.
Rego, R.A.
Carrito, B.
Pais, A.
Bento, M.J.
Rodrigues, J.
Lourenço, A.
Mayer-da-Silva, A.
Coza, D.
Todescu, A.I.
Valkov, M.Y.
Gusenkova, L.
Lazarevich, O.
Prudnikova, O.
Vjushkov, D.M.
Egorova, A.
Orlov, A.
Pikalova, L.V.
Zhuikova, L.D.
Adamcik, J.
Safaei Diba, C.
Zadnik, V.
Žagar, T.
De-La-Cruz, M.
Lopez-de-Munain, A.
Aleman, A.
Rojas, D.
Chillarón, R.J.
Navarro, AIM
Marcos-Gragera, R.
Puigdemont, M.
Rodríguez-Barranco, M.
Sánchez Perez, M.J.
Franch Sureda, P.
Ramos Montserrat, M.
Chirlaque López, M.D.
Sánchez Gil, A.
Ardanaz, E.
Guevara, M.
Cañete-Nieto, A.
Peris-Bonet, R.
Carulla, M.
Galceran, J.
Almela, F.
Sabater, C.
Khan, S.
Pettersson, D.
Dickman, P.
Staehelin, K.
Struchen, B.
Egger Hayoz, C.
Rapiti, E.
Schaffar, R.
Went, P.
Mousavi, S.M.
Bulliard, J.L.
Maspoli-Conconi, M.
Kuehni, C.E.
Redmond, S.M.
Bordoni, A.
Ortelli, L.
Chiolero, A.
Konzelmann, I.
Rohrmann, S.
Wanner, M.
Broggio, J.
Rashbass, J.
Stiller, C.
Fitzpatrick, D.
Gavin, A.
Morrison, D.S.
Thomson, C.S.
Greene, G.
Huws, D.W.
Grayson, M.
Rawcliffe, H.
Allemani, C.
Coleman, M.P.
Di Carlo, V.
Girardi, F.
Matz, M.
Minicozzi, P.
Sanz, N.
Ssenyonga, N.
James, D.
Stephens, R.
Chalker, E.
Smith, M.
Gugusheff, J.
You, H.
Qin Li, S.
Dugdale, S.
Moore, J.
Philpot, S.
Pfeiffer, R.
Thomas, H.
Silva Ragaini, B.
Venn, A.J.
Evans, S.M.
Te Marvelde, L.
Savietto, V.
Trevithick, R.
Aitken, J.
Currow, D.
Fowler, C.
Lewis, C.
Groupes de travail
CONCORD Working Group
Liens vers les personnes
Liens vers les unités
ISSN
1523-5866
Statut éditorial
Publié
Date de publication
2023-03-14
Volume
25
Numéro
3
Première page
580
Dernière page/numéro d’article
592
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Survival is a key metric of the effectiveness of a health system in managing cancer. We set out to provide a comprehensive examination of worldwide variation and trends in survival from brain tumors in adults, by histology.
We analyzed individual data for adults (15-99 years) diagnosed with a brain tumor (ICD-O-3 topography code C71) during 2000-2014, regardless of tumor behavior. Data underwent a 3-phase quality control as part of CONCORD-3. We estimated net survival for 11 histology groups, using the unbiased nonparametric Pohar Perme estimator.
The study included 556,237 adults. In 2010-2014, the global range in age-standardized 5-year net survival for the most common sub-types was broad: in the range 20%-38% for diffuse and anaplastic astrocytoma, from 4% to 17% for glioblastoma, and between 32% and 69% for oligodendroglioma. For patients with glioblastoma, the largest gains in survival occurred between 2000-2004 and 2005-2009. These improvements were more noticeable among adults diagnosed aged 40-70 years than among younger adults.
To the best of our knowledge, this study provides the largest account to date of global trends in population-based survival for brain tumors by histology in adults. We have highlighted remarkable gains in 5-year survival from glioblastoma since 2005, providing large-scale empirical evidence on the uptake of chemoradiation at population level. Worldwide, survival improvements have been extensive, but some countries still lag behind. Our findings may help clinicians involved in national and international tumor pathway boards to promote initiatives aimed at more extensive implementation of clinical guidelines.
We analyzed individual data for adults (15-99 years) diagnosed with a brain tumor (ICD-O-3 topography code C71) during 2000-2014, regardless of tumor behavior. Data underwent a 3-phase quality control as part of CONCORD-3. We estimated net survival for 11 histology groups, using the unbiased nonparametric Pohar Perme estimator.
The study included 556,237 adults. In 2010-2014, the global range in age-standardized 5-year net survival for the most common sub-types was broad: in the range 20%-38% for diffuse and anaplastic astrocytoma, from 4% to 17% for glioblastoma, and between 32% and 69% for oligodendroglioma. For patients with glioblastoma, the largest gains in survival occurred between 2000-2004 and 2005-2009. These improvements were more noticeable among adults diagnosed aged 40-70 years than among younger adults.
To the best of our knowledge, this study provides the largest account to date of global trends in population-based survival for brain tumors by histology in adults. We have highlighted remarkable gains in 5-year survival from glioblastoma since 2005, providing large-scale empirical evidence on the uptake of chemoradiation at population level. Worldwide, survival improvements have been extensive, but some countries still lag behind. Our findings may help clinicians involved in national and international tumor pathway boards to promote initiatives aimed at more extensive implementation of clinical guidelines.
PID Serval
serval:BIB_CAEEFCAA5AB6
PMID
Open Access
Oui
Date de création
2022-12-01T13:37:46.655Z
Date de création dans IRIS
2025-05-20T22:45:12Z
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Nom
36355361_BIB_CAEEFCAA5AB6.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by-nc/4.0
Taille
286.35 KB
Format
Adobe PDF
PID Serval
serval:BIB_CAEEFCAA5AB6.P001
URN
urn:nbn:ch:serval-BIB_CAEEFCAA5AB66
Somme de contrôle
(MD5):6cd919599f12c6083808f2400c8d8e76