Titre
Osteomalacia revealing celiac disease and primary biliary cirrhosis-related Fanconi syndrome in a patient with systemic sclerosis
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Terrier, B.
Auteure/Auteur
Fakhouri, F.
Auteure/Auteur
Berezne, A.
Auteure/Auteur
Bouldouyre, M. A.
Auteure/Auteur
Guilpain, P.
Auteure/Auteur
Sogni, P.
Auteure/Auteur
Terris, B.
Auteure/Auteur
Noel, L. H.
Auteure/Auteur
Guillevin, L.
Auteure/Auteur
Mouthon, L.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0392-856X
Statut éditorial
Publié
Date de publication
2008
Volume
26
Numéro
3
Première page
467
Dernière page/numéro d’article
70
Langue
anglais
Notes
Terrier, B
Fakhouri, F
Berezne, A
Bouldouyre, M-A
Guilpain, P
Sogni, P
Terris, B
Noel, L-H
Guillevin, L
Mouthon, L
eng
Case Reports
Italy
Clin Exp Rheumatol. 2008 May-Jun;26(3):467-70.
Fakhouri, F
Berezne, A
Bouldouyre, M-A
Guilpain, P
Sogni, P
Terris, B
Noel, L-H
Guillevin, L
Mouthon, L
eng
Case Reports
Italy
Clin Exp Rheumatol. 2008 May-Jun;26(3):467-70.
Résumé
Systemic sclerosis (SSc) may affect the gastrointestinal tract and cause very rarely malabsorption syndrome related to bacterial overgrowth. Malabsorption syndrome may be responsible for weight loss, diarrhea, osteomalacia, and iron and vitamins deficiency. We report the case of a SSc patient who developed osteomalacia caused by the combination of two exceptional conditions in the setting of SSc: celiac disease (CD) and primary biliary cirrhosis (PBC)-related Fanconi syndrome. Oral prednisone with angiotensin-converting enzyme inhibitors, was initiated because of active lesions of tubulitis, and led to the complete regression of bone pains, and by the improvement of renal function and regression of the features of proximal tubulopathy. Thus, in the presence of vitamin deficiencies in a patient with SSc, together with a search for malabsorption syndrome secondary to bacterial overgrowth, CD and/or PBC-associated Fanconi syndrome should be investigated.
PID Serval
serval:BIB_F6F8BCAD3980
PMID
Date de création
2022-03-01T09:18:20.031Z
Date de création dans IRIS
2025-05-21T06:43:09Z