Titre
The response of adult and developing rat plantaris muscle to overload
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Frischknecht, R.
Auteure/Auteur
Belverstone, D.
Auteure/Auteur
Vrbova, G.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0031-6768
Statut éditorial
Publié
Date de publication
1995-12
Volume
431
Numéro
2
Première page
204
Dernière page/numéro d’article
211
Peer-reviewed
Oui
Langue
anglais
Résumé
The effect of overload on the rat plantaris muscle was studied in animals of different ages. Overload was induced by removal of gastrocnemius and soleus muscles. As expected, when the operation was carried out in adults, the plantaris muscle became heavier and stronger. These changes occured within 30 days after the operation. In animals in which the operation was carried out 1-12 days after birth and the muscle examined 6-20 weeks later, different results were obtained. In the group operated at 1-9 days of age, the muscles developed a lower maximal twitch and tetanic tension than the contralateral plantaris muscle. There was no difference in the time to peak or muscle weight between the overloaded and the contralateral muscles. Similar changes were observed in animals where the overload was induced at 11 or 12 days of age except for the weight which was significantly higher than that of the control plantaris muscles. The number of slow fibers increased in animals where overload was induced 11-12 days postnatally or in adults, but not when muscles were overloaded at 9 days of age. The possible reasons for the different response of adult and neonatal muscles to overload are discussed.
Sujets
PID Serval
serval:BIB_008FABBA4F9D
PMID
Date de création
2008-01-25T07:34:33.537Z
Date de création dans IRIS
2025-05-20T15:33:16Z