Titre
Anatomic constraints on cognitive theories of category specificity.
Type
article
Institution
Externe
Périodique
Auteur(s)
Devlin, J.T.
Auteure/Auteur
Moore, C.J.
Auteure/Auteur
Mummery, C.J.
Auteure/Auteur
Gorno-Tempini, M.L.
Auteure/Auteur
Phillips, J.A.
Auteure/Auteur
Noppeney, U.
Auteure/Auteur
Frackowiak, R.S.
Auteure/Auteur
Friston, K.J.
Auteure/Auteur
Price, C.J.
Auteure/Auteur
Liens vers les personnes
ISSN
1053-8119
Statut éditorial
Publié
Date de publication
2002
Volume
15
Numéro
3
Première page
675
Dernière page/numéro d’article
685
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
Many cognitive theories of semantic organization stem from reports of patients with selective, category-specific deficits for particular classes of objects (e.g., fruit). The anatomical assumptions underlying the competing claims can be evaluated with functional neuroimaging but the findings to date have been inconsistent and insignificant when standard statistical criteria are adopted. We hypothesized that category differences in functional brain responses might be small and task dependent. To test this hypothesis, we entered data from seven PET studies into a single multifactorial design which crossed category (living vs man-made) with a range of tasks. Reliable category-specific effects were observed but only for word retrieval and semantic decision tasks. Living things activated medial aspects of the anterior temporal poles bilaterally while tools activated a left posterior middle temporal region. These category-by-task interactions provide robust evidence for an anatomical double dissociation according to category and place strong constraints on cognitive theories of the semantic system. Furthermore they reconcile some of the apparent inconsistencies between lesion studies and functional neuroimaging data.
Sujets
PID Serval
serval:BIB_8608396BAA6F
PMID
Date de création
2011-09-12T16:37:52.279Z
Date de création dans IRIS
2025-05-21T04:19:33Z