Titre
Cell division ring, a new cell division protein and vertical inheritance of a bacterial organelle in anammox planctomycetes.
Type
article
Institution
Externe
Périodique
Auteur(s)
van Niftrik, L.
Auteure/Auteur
Geerts, W.J.
Auteure/Auteur
van Donselaar, E.G.
Auteure/Auteur
Humbel, B.M.
Auteure/Auteur
Webb, R.I.
Auteure/Auteur
Harhangi, H.R.
Auteure/Auteur
Camp, H.J.
Auteure/Auteur
Fuerst, J.A.
Auteure/Auteur
Verkleij, A.J.
Auteure/Auteur
Jetten, M.S.
Auteure/Auteur
Strous, M.
Auteure/Auteur
Liens vers les personnes
ISSN
1365-2958
Statut éditorial
Publié
Date de publication
2009
Volume
73
Numéro
6
Première page
1009
Dernière page/numéro d’article
1019
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Anammox bacteria are members of the phylum Planctomycetes that oxidize ammonium anaerobically and produce a significant part of the atmosphere's dinitrogen gas. They contain a unique bacterial organelle, the anammoxosome, which is the locus of anammox catabolism. While studying anammox cell and anammoxosome division with transmission electron microscopy including electron tomography, we observed a cell division ring in the outermost compartment of dividing anammox cells. In most Bacteria, GTP hydrolysis drives the tubulin-analogue FtsZ to assemble into a ring-like structure at the cell division site where it functions as a scaffold for the molecular machinery that performs cell division. However, the genome of the anammox bacterium 'Candidatus Kuenenia stuttgartiensis' does not encode ftsZ. Genomic analysis of open reading frames with potential GTPase activity indicated a possible novel cell division ring gene: kustd1438, which was unrelated to ftsZ. Immunogold localization specifically localized kustd1438 to the cell division ring. Genomic analyses of other members of the phyla Planctomycetes and Chlamydiae revealed no putative functional homologues of kustd1438, suggesting that it is specific to anammox bacteria. Electron tomography also revealed that the bacterial organelle was elongated along with the rest of the cell and divided equally among daughter cells during the cell division process.
Sujets
PID Serval
serval:BIB_30A1F70737BD
PMID
Date de création
2012-02-27T09:39:48.392Z
Date de création dans IRIS
2025-05-20T18:47:02Z