Titre
Vena cava filters in patients presenting with major bleeding during anticoagulation for venous thromboembolism.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Mellado, M.
Auteure/Auteur
Trujillo-Santos, J.
Auteure/Auteur
Bikdeli, B.
Auteure/Auteur
Jiménez, D.
Auteure/Auteur
Núñez, M.J.
Auteure/Auteur
Ellis, M.
Auteure/Auteur
Marchena, P.J.
Auteure/Auteur
Vela, J.R.
Auteure/Auteur
Clara, A.
Auteure/Auteur
Moustafa, F.
Auteure/Auteur
Monreal, M.
Auteure/Auteur
Contributrices/contributeurs
Adarraga, M.D.
Aibar, M.A.
Alfonso, M.
Arcelus, J.I.
Ballaz, A.
Baños, P.
Barba, R.
Barrón, M.
Bascuñana, J.
Blanco-Molina, A.
Camon, A.M.
Carrasco, C.
Chasco, L.
Cruzs, A.J.
Del Pozo, R.
Del Toro, J.
Díaz-Pedroche, M.C.
Díaz-Peromingo, J.A.
Encabo, M.
Falgá, C.
Fernández-Aracil, C.
Fernández-Capitán, C.
Fidalgo, M.A.
Font, C.
Font, L.
Furest, I.
García, M.A.
García-Bragado, F.
García-Morillo, M.
García-Raso, A.
García-Sánchez, I.
Gavín, O.
Gómez, C.
Gómez, V.
González, J.
Grau, E.
Guijarro, R.
Guirado, L.
Gutiérrez, J.
Hernández-Blasco, L.
Hernando, E.
Isern, V.
Jara-Palomares, L.
Jaras, M.J.
Jiménez, D.
Joya, M.D.
Lima, J.
Llamas, P.
Lobo, J.L.
López-Jiménez, L.
López-Reyes, R.
López-Sáez, J.B.
Lorente, M.A.
Lorenzo, A.
Loring, M.
Lumbierres, M.
Madridano, O.
Maestre, A.
Marchena, P.J.
Martín, M.
Martín-Martos, F.
Mellado, M.
Monreal, M.
Morales, M.V.
Nieto, J.A.
Núñez, M.J.
Olivares, M.C.
Otalora, S.
Otero, R.
Pedrajas, J.M.
Pellejero, G.
Pérez-Ductor, C.
Peris, M.L.
Pons, I.
Porras, J.A.
Riera-Mestre, A.
Rivas, A.
Rodríguez-Dávila, M.A.
Rodríguez-Galán, I.
Rosa, V.
Rubio, C.M.
Ruiz-Artacho, P.
Sahuquillo, J.C.
Sala-Sainz, M.C.
Sampériz, A.
Sánchez-Artola, B.
Sánchez-Martínez, R.
Sancho, T.
Soler, S.
Soto, M.J.
Suriñach, J.M.
Tolosa, C.
Torres, M.I.
Trujillo-Santos, J.
Uresandi, F.
Usandizaga, E.
Valero, B.
Valle, R.
Vela, J.
Vidal, G.
Villalobos, A.
Xifre, B.
Vázquez, F.J.
Vilaseca, A.
Vanassche, T.
Vandenbriele, C.
Verhamme, P.
Yoo, HHB
Wells, P.
Hirmerova, J.
Malý, R.
Salgado, E.
Benzidia, I.
Bertoletti, L.
Bura-Riviere, A.
Falvo, N.
Farge-Bancel, D.
Hij, A.
Merah, A.
Mahé, I.
Moustafa, F.
Quere, I.
Braester, A.
Brenner, B.
Ellis, M.
Tzoran, I.
Antonucci, G.
Bilora, F.
Bucherini, E.
Cattabiani, C.
Ciammaichella, M.
Dentali, F.
Di Micco, P.
Doddi, M.
Duce, R.
Giorgi-Pierfranceschi, M.
Grandone, E.
Imbalzano, E.
Lessiani, G.
Maggi, F.
Maida, R.
Mastroiacovo, D.
Pace, F.
Pesavento, R.
Poggio, R.
Prandoni, P.
Quintavalla, R.
Rocci, A.
Siniscalchi, C.
Tiraferri, E.
Tonello, D.
Visonà, A.
Zalunardo, B.
Gibietis, V.
Skride, A.
Vitola, B.
Zdraveska, M.
Bounameaux, H.
Calanca, L.
Fresa, M.
Mazzolai, L.
Bikdeli, B.
Groupes de travail
RIETE Investigators
Liens vers les personnes
Liens vers les unités
ISSN
1970-9366
Statut éditorial
Publié
Date de publication
2019-10
Volume
14
Numéro
7
Première page
1101
Dernière page/numéro d’article
1112
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
The association between inferior vena cava filter (IVC) use and outcome in patients presenting with major bleeding during anticoagulation for venous thromboembolism (VTE) has not been thoroughly investigated. We used the RIETE registry to compare the 30-day outcomes (death, major re-bleeding or VTE recurrences) in VTE patients who bled during the first 3 months of therapy, regarding the insertion of an IVC filter. A propensity score matched (PSM) analysis was performed to adjust for potential confounders. From January 2001 to September 2016, 1065 VTE patients had major bleeding during the first 3 months of anticoagulation (gastrointestinal 370; intracranial 124). Of these, 122 patients (11%) received an IVC filter. Patients receiving a filter restarted anticoagulation later (median, 4 vs. 2 days) and at lower doses (95 ± 52 IU/kg/day vs. 104 ± 55 of low-molecular-weight heparin) than those not receiving a filter. During the first 30 days after bleeding (after excluding 246 patients who died within the first 24 h), 283 patients (27%) died, 63 (5.9%) had non-fatal re-bleeding and 19 (1.8%) had recurrent pulmonary embolism (PE). In PSM analysis, patients receiving an IVC filter (n = 122) had a lower risk for all-cause death (HR 0.49; 95% CI 0.31-0.77) or fatal bleeding (HR 0.16; 95% CI 0.07-0.49) and a similar risk for re-bleeding (HR 0.55; 95% CI 0.23-1.40) or PE recurrences (HR 1.57; 95% CI 0.38-6.36) than those not receiving a filter (n = 429). In VTE patients experiencing major bleeding during the first 3 months, use of an IVC filter was associated with reduced mortality rates.Clinical Trial Registration NCT02832245.
Sujets
PID Serval
serval:BIB_521B69BF3577
PMID
Date de création
2020-11-26T11:03:15.446Z
Date de création dans IRIS
2025-05-20T15:37:43Z