Titre
Postoperative subconjunctival mitomycin-C injection after non-penetrating glaucoma surgery.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Iester, M.
Auteure/Auteur
Ravinet, E.
Auteure/Auteur
Mermoud, A.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1080-7683
Statut éditorial
Publié
Date de publication
2002
Volume
18
Numéro
4
Première page
307
Dernière page/numéro d’article
312
Peer-reviewed
Oui
Langue
anglais
Résumé
PURPOSE: To evaluate subconjunctival mitomycin C (MMC) injection efficacy and safety in patients with failing glaucoma non-penetrating filtering blebs. METHODS: Twenty-eight eyes were consecutively recruited for this study. Only one eye for each patient was randomly selected. All the recruited patients had glaucoma and uncontrolled intraocular pressure after a non-penetrating filtering glaucoma surgery and/or a pathological aspect of the filtering bleb (i.e., vascularized and/or encysted). One or more MMC injections were performed under the conjunctiva closed to the bleb to improve filtration. Local effects and complications of subconjunctival MMC injections were analyzed. RESULTS: Out of the 28 patients, 21 (75%) had MMC also applied intraoperatively. The mean postoperative IOP before MMC injections was 17 +/- 6.6 mmHg. The final IOP after MMC injections was 13.9 +/- 2.9 mmHg after a mean follow-up of 6 months. A total of 67 subconjunctival MMC injections were performed with a mean of 2.9 (ranging from 1 to 5) injections per patient. The only complication found to be possibly related to MMC injections was two cases of corneal Dellen. CONCLUSION: From these preliminary results, subconjunctival MMC injections in selected cases appear to be not only safe but also effective in promoting further the postoperative IOP drop.
PID Serval
serval:BIB_63553551086E
PMID
Date de création
2008-02-28T12:01:50.682Z
Date de création dans IRIS
2025-05-21T04:01:27Z