Titre
Health-related quality of life in older patients surviving ICU treatment for COVID-19: results from an international observational study of patients older than 70 years.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Soliman, I.W.
Auteure/Auteur
Leaver, S.
Auteure/Auteur
Flaatten, H.
Auteure/Auteur
Fjølner, J.
Auteure/Auteur
Wernly, B.
Auteure/Auteur
Bruno, R.R.
Auteure/Auteur
Artigas, A.
Auteure/Auteur
Bollen Pinto, B.
Auteure/Auteur
Schefold, J.C.
Auteure/Auteur
Beil, M.
Auteure/Auteur
Sviri, S.
Auteure/Auteur
van Heerden, P.V.
Auteure/Auteur
Szczeklik, W.
Auteure/Auteur
Elhadi, M.
Auteure/Auteur
Joannidis, M.
Auteure/Auteur
Oeyen, S.
Auteure/Auteur
Zafeiridis, T.
Auteure/Auteur
Wollborn, J.
Auteure/Auteur
Banzo, MJA
Auteure/Auteur
Fuest, K.
Auteure/Auteur
Marsh, B.
Auteure/Auteur
Andersen, F.H.
Auteure/Auteur
Moreno, R.
Auteure/Auteur
Boumendil, A.
Auteure/Auteur
Guidet, B.
Auteure/Auteur
Jung, C.
Auteure/Auteur
De Lange, D.W.
Auteure/Auteur
Contributrices/contributeurs
Eller, P.
Joannidis, M.
Mesotten, D.
Reper, P.
Oeyen, S.
Swinnen, W.
Brix, H.
Brushoej, J.
Villefrance, M.
Nedergaard, H.K.
Bjerregaard, A.T.
Balleby, I.R.
Andersen, K.
Hansen, M.A.
Uhrenholt, S.
Bundgaard, H.
Fjølner, J.
Mohamed, AAH
Salah, R.
Ali, YKNM
Wassim, K.
Elgazzar, Y.A.
Tharwat, S.
Azzam, A.Y.
Habib, A.A.
Abosheaishaa, H.M.
Azab, M.A.
Leaver, S.
Galbois, A.
Guidet, B.
Charron, C.
Guerot, E.
Besch, G.
Rigaud, J.P.
Maizel, J.
Djibré, M.
Burtin, P.
Garcon, P.
Nseir, S.
Valette, X.
Alexandru, N.
Marin, N.
Vaissiere, M.
Plantefeve, G.
Vanderlinden, T.
Jurcisin, I.
Megarbane, B.
Caillard, A.
Valent, A.
Garnier, M.
Besset, S.
Oziel, J.
Raphaelen, J.H.
Dauger, S.
Dumas, G.
Goncalves, B.
Piton, G.
Jung, C.
Bruno, R.R.
Kelm, M.
Wolff, G.
Barth, E.
Goebel, U.
Barth, E.
Kunstein, A.
Schuster, M.
Welte, M.
Lutz, M.
Meybohm, P.
Steiner, S.
Poerner, T.
Haake, H.
Schaller, S.
Kindgen-Milles, D.
Meyer, C.
Kurt, M.
Kuhn, K.F.
Randerath, W.
Wollborn, J.
Dindane, Z.
Kabitz, H.J.
Voigt, I.
Shala, G.
Faltlhauser, A.
Rovina, N.
Aidoni, Z.
Chrisanthopoulou, E.
Papadogoulas, A.
Gurjar, M.
Mahmoodpoor, A.
Ahmed, A.K.
Marsh, B.
Elsaka, A.
Sviri, S.
Comellini, V.
Rabha, A.
Ahmed, H.
Namendys-Silva, S.A.
Ghannam, A.
Groenendijk, M.
Zegers, M.
de Lange, D.
Cornet, A.
Evers, M.
Haas, L.
Dormans, T.
Dieperink, W.
Romundstad, L.
Sjøbø, B.
Andersen, F.H.
Strietzel, H.F.
Olasveengen, T.
Hahn, M.
Czuczwar, M.
Gawda, R.
Klimkiewicz, J.
de LurdesSantos, M.C.
Gordinho, A.
Santos, H.
Assis, R.
Oliveira, AIP
Badawy, M.R.
Perez-Torres, D.
Gomà, G.
Villamayor, M.I.
Mira, A.P.
Cubero, P.J.
Rivera, S.A.
Tomasa, T.
Iglesias, D.
Vázquez, E.M.
Aldecoa, C.
Ferreira, A.F.
Zalba-Etayo, B.
Canas-Perez, I.
Tamayo-Lomas, L.
Diaz-Rodriguez, C.
Sancho, S.
Priego, J.
Abualqumboz, EMY
Hilles, MMY
Saleh, M.
Ben-HAmouda, N.
Roberti, A.
Dullenkopf, A.
Fleury, Y.
Pinto, B.B.
Schefold, J.C.
Al-Sadawi, M.
Serck, N.
Dewaele, E.
Kumar, P.
Bundesen, C.
Innes, R.
Gooch, J.
Cagova, L.
Potter, E.
Reay, M.
Davey, M.
Humphreys, S.
Berlemont, C.H.
Chousterman, B.G.
Dépret, F.
Ferre, A.
Vettoretti, L.
Thevenin, D.
Faltlhauser, A.
Milovanovic, M.
Simon, P.
Lorenz, M.
Stoll, S.E.
Dubler, S.
Fuest, K.
Mulita, F.
Kondili, E.
Andrianopoulos, I.
Meynaar, I.
Cornet, A.D.
Sjøbøe, B.
Kluzik, A.
Zatorski, P.
Drygalski, T.
Szczeklik, W.
Solek-Pastuszka, J.
Onichimowski, D.
Stefaniak, J.
Stefanska-Wronka, K.
Zabul, E.
Cardoso, F.S.
Banzo, MJA
Tomasa-Irriguible, T.M.
Mira, Á.P.
Arias-Rivera, S.
Frutos-Vivar, F.
Lopez-Cuenca, S.
de Gopegui, P.R.
Abidi, N.
Chau, I.
Pugh, R.
Smuts, S.
Groupes de travail
COVIP-study group
Liens vers les personnes
Liens vers les unités
ISSN
1468-2834
Statut éditorial
Publié
Date de publication
2022-02-02
Volume
51
Numéro
2
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Observational Study
Publication Status: ppublish
Publication Status: ppublish
Résumé
health-related quality of life (HRQoL) is an important patient-centred outcome in patients surviving ICU admission for COVID-19. It is currently not clear which domains of the HRQoL are most affected.
to quantify HRQoL in order to identify areas of interventions.
prospective observation study.
admissions to European ICUs between March 2020 and February 2021.
patients aged 70 years or older admitted with COVID-19 disease.
collected determinants include SOFA-score, Clinical Frailty Scale (CFS), number and timing of ICU procedures and limitation of care, Katz Activities of Daily Living (ADL) dependence score. HRQoL was assessed at 3 months after ICU admission with the Euro-QoL-5D-5L questionnaire. An outcome of ≥4 on any of Euro-QoL-5D-5L domains was considered unfavourable.
in total 3,140 patients from 14 European countries were included in this study. Three months after inclusion, 1,224 patients (39.0%) were alive and the EQ-5D-5L from was obtained. The CFS was associated with an increased odds ratio for an unfavourable HRQoL outcome after 3 months; OR 1.15 (95% confidence interval (CI): 0.71-1.87) for CFS 2 to OR 4.33 (95% CI: 1.57-11.9) for CFS ≧ 7. The Katz ADL was not statistically significantly associated with HRQoL after 3 months.
in critically ill old intensive care patients suffering from COVID-19, the CFS is associated with the subjectively perceived quality of life. The CFS on admission can be used to inform patients and relatives on the risk of an unfavourable qualitative outcome if such patients survive.
to quantify HRQoL in order to identify areas of interventions.
prospective observation study.
admissions to European ICUs between March 2020 and February 2021.
patients aged 70 years or older admitted with COVID-19 disease.
collected determinants include SOFA-score, Clinical Frailty Scale (CFS), number and timing of ICU procedures and limitation of care, Katz Activities of Daily Living (ADL) dependence score. HRQoL was assessed at 3 months after ICU admission with the Euro-QoL-5D-5L questionnaire. An outcome of ≥4 on any of Euro-QoL-5D-5L domains was considered unfavourable.
in total 3,140 patients from 14 European countries were included in this study. Three months after inclusion, 1,224 patients (39.0%) were alive and the EQ-5D-5L from was obtained. The CFS was associated with an increased odds ratio for an unfavourable HRQoL outcome after 3 months; OR 1.15 (95% confidence interval (CI): 0.71-1.87) for CFS 2 to OR 4.33 (95% CI: 1.57-11.9) for CFS ≧ 7. The Katz ADL was not statistically significantly associated with HRQoL after 3 months.
in critically ill old intensive care patients suffering from COVID-19, the CFS is associated with the subjectively perceived quality of life. The CFS on admission can be used to inform patients and relatives on the risk of an unfavourable qualitative outcome if such patients survive.
PID Serval
serval:BIB_EBBCE7929B63
PMID
Open Access
Oui
Date de création
2022-03-03T19:17:59.004Z
Date de création dans IRIS
2025-05-21T07:06:54Z
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Nom
35136896_BIB_EBBCE7929B63.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by-nc/4.0
Taille
457.95 KB
Format
Adobe PDF
PID Serval
serval:BIB_EBBCE7929B63.P001
URN
urn:nbn:ch:serval-BIB_EBBCE7929B632
Somme de contrôle
(MD5):40a8c7026fe992ede4e3038c247fc2a1