Titre
Application of postmortem imaging modalities in cases of sudden death due to cardiovascular diseases-current achievements and limitations from a pathology perspective : Endorsed by the Association for European Cardiovascular Pathology and by the International Society of Forensic Radiology and Imaging.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Michaud, K.
Auteure/Auteur
Jacobsen, C.
Auteure/Auteur
Basso, C.
Auteure/Auteur
Banner, J.
Auteure/Auteur
Blokker, B.M.
Auteure/Auteur
de Boer, H.H.
Auteure/Auteur
Dedouit, F.
Auteure/Auteur
O'Donnell, C.
Auteure/Auteur
Giordano, C.
Auteure/Auteur
Magnin, V.
Auteure/Auteur
Grabherr, S.
Auteure/Auteur
Suvarna, S.K.
Auteure/Auteur
Wozniak, K.
Auteure/Auteur
Parsons, S.
Auteure/Auteur
van der Wal, A.C.
Auteure/Auteur
Liens vers les personnes
ISSN
1432-2307
Statut éditorial
Publié
Date de publication
2023-02
Volume
482
Numéro
2
Première page
385
Dernière page/numéro d’article
406
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Postmortem imaging (PMI) is increasingly used in postmortem practice and is considered a potential alternative to a conventional autopsy, particularly in case of sudden cardiac deaths (SCD). In 2017, the Association for European Cardiovascular Pathology (AECVP) published guidelines on how to perform an autopsy in such cases, which is still considered the gold standard, but the diagnostic value of PMI herein was not analyzed in detail. At present, significant progress has been made in the PMI diagnosis of acute ischemic heart disease, the most important cause of SCD, while the introduction of postmortem CT angiography (PMCTA) has improved the visualization of several parameters of coronary artery pathology that can support a diagnosis of SCD. Postmortem magnetic resonance (PMMR) allows the detection of acute myocardial injury-related edema. However, PMI has limitations when compared to clinical imaging, which severely impacts the postmortem diagnosis of myocardial injuries (ischemic versus non-ischemic), the age-dating of coronary occlusion (acute versus old), other potentially SCD-related cardiac lesions (e.g., the distinctive morphologies of cardiomyopathies), aortic diseases underlying dissection or rupture, or pulmonary embolism. In these instances, PMI cannot replace a histopathological examination for a final diagnosis. Emerging minimally invasive techniques at PMI such as image-guided biopsies of the myocardium or the aorta, provide promising results that warrant further investigations. The rapid developments in the field of postmortem imaging imply that the diagnosis of sudden death due to cardiovascular diseases will soon require detailed knowledge of both postmortem radiology and of pathology.
PID Serval
serval:BIB_4B754DC66E72
PMID
Open Access
Oui
Date de création
2023-01-03T14:42:51.224Z
Date de création dans IRIS
2025-05-20T20:21:40Z
Fichier(s)![Vignette d'image]()
En cours de chargement...
Nom
s00428-022-03458-6.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
1.9 MB
Format
Adobe PDF
PID Serval
serval:BIB_4B754DC66E72.P001
URN
urn:nbn:ch:serval-BIB_4B754DC66E722
Somme de contrôle
(MD5):af6f5abd9a272b3807c9020a16504b57