Titre
Impact of 2011 French guidelines on antibiotic prescription for acute otitis media in infants
Type
article
Institution
Externe
Périodique
Auteur(s)
Levy, C.
Auteure/Auteur
Pereira, M.
Auteure/Auteur
Guedj, R.
Auteure/Auteur
Abt-Nord, C.
Auteure/Auteur
Gelbert, N. B.
Auteure/Auteur
Cohen, R.
Auteure/Auteur
Alberti, C.
Auteure/Auteur
Gajdos, V.
Auteure/Auteur
Angoulvant, F.
Auteure/Auteur
Liens vers les personnes
ISSN
1769-6690
Statut éditorial
Publié
Date de publication
2014-03
Volume
44
Numéro
3
Première page
102
Dernière page/numéro d’article
6
Langue
anglais
Notes
Levy, C
Pereira, M
Guedj, R
Abt-Nord, C
Gelbert, N Baudino
Cohen, R
Alberti, C
Gajdos, V
Angoulvant, F
eng
Research Support, Non-U.S. Gov't
France
2014/03/19
Med Mal Infect. 2014 Mar;44(3):102-6. doi: 10.1016/j.medmal.2014.01.005. Epub 2014 Mar 11.
Pereira, M
Guedj, R
Abt-Nord, C
Gelbert, N Baudino
Cohen, R
Alberti, C
Gajdos, V
Angoulvant, F
eng
Research Support, Non-U.S. Gov't
France
2014/03/19
Med Mal Infect. 2014 Mar;44(3):102-6. doi: 10.1016/j.medmal.2014.01.005. Epub 2014 Mar 11.
Résumé
OBJECTIVE: In 2011, new guidelines on antibiotic prescription for acute otitis media (AOM) were published in France to decrease the use of third generation cephalosporins that promote the carriage of extended-spectrum beta-lactamase producing Escherichia coli. Our objective was to assess the impact of the 2011 French recommendations on the type of antibiotics prescribed for AOM. METHODS: Fourteen thousand six hundred and sixty-one children, 6 to 24 months of age, presenting with AOM were included in 2 studies, between November 1, 2009 and October 31, 2012. The first one was conducted with the support of 62 private practice pediatricians; the second one was conducted in 7 pediatric emergency departments. Three periods of 1 year each were defined. RESULTS: Antibiotics were prescribed in 12,471 (85.1%) of cases of AOM during the study period. Amoxicillin prescriptions was multiplied by 25, between the first year (2.6%) and the last year (66.1%). Conversely, prescriptions of cefpodoxime proxetil and amoxicillin-clavulanic acid decreased from 33.6% and 62.0% in the first year to 5.2% and 27.7% in the last year, respectively. This trend was observed in both private practices and in the pediatric emergency departments. CONCLUSION: Amoxicillin became the most frequently prescribed antibiotic for AOM in 2012, complying with the 2011 French guidelines, while the proportion of prescribed broad-spectrum antibiotics decreased. Our study highlights the importance of guidelines to decrease the prescription of broad-spectrum antibiotics, a crucial factor in the prevention of antibiotic resistance.
Sujets
PID Serval
serval:BIB_C82210F267AA
PMID
Date de création
2025-02-07T17:24:40.339Z
Date de création dans IRIS
2025-05-21T03:58:12Z