Titre
Eingeschränkte Nierenfunktion bei Lithium-Therapie [Impaired kidney function in lithium therapy].
Type
article
Institution
Externe
Périodique
Therapeutische Umschau. Revue Thérapeutique
Auteur(s)
Gabutti, L.
Auteure/Auteur
Gugger, M.
Auteure/Auteur
Marti, H.P.
Auteure/Auteur
Liens vers les personnes
ISSN
0040-5930
Statut éditorial
Publié
Date de publication
1998
Volume
55
Numéro
9
Première page
562
Dernière page/numéro d’article
564
Langue
allemand
Notes
Publication types: Case Reports ; English Abstract ; Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
Long-term therapy with lithium may be associated with a broad spectrum of functional and structural side-effects in the kidney. Among these features, nephrogenic diabetes insipidus is the most frequent and it can be expected to occur in 20-70% of the patients. Diabetes insipidus is the result of a lithium induced resistance of collecting ducts to antidiuretic hormone. Additional functional disturbances are represented by renal tubular acidosis and consequences of hypercalcemia. Structural alterations of the kidney have a rare occurrence. In the literature, there are accounts of chronic tubulo-interstitial nephritis, acute tubular necrosis and few cases of glomerulopathies. Our report of a patient with chronic interstital nephritis is supplemented by a brief discussion of the diverse picture of the nephrotoxicity of lithium.
PID Serval
serval:BIB_A5FC2F30EAB6
PMID
Date de création
2013-06-19T10:23:55.440Z
Date de création dans IRIS
2025-05-21T03:25:46Z