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  4. The role of 18F-FDG-PET and PET/CT in patients with sarcoidosis: an updated evidence-based review.
 
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Titre

The role of 18F-FDG-PET and PET/CT in patients with sarcoidosis: an updated evidence-based review.

Type
synthèse (review)
Institution
Externe
Périodique
Academic radiology  
Auteur(s)
Treglia, G.
Auteure/Auteur
Annunziata, S.
Auteure/Auteur
Sobic-Saranovic, D.
Auteure/Auteur
Bertagna, F.
Auteure/Auteur
Caldarella, C.
Auteure/Auteur
Giovanella, L.
Auteure/Auteur
Liens vers les personnes
Treglia, Giorgio  
ISSN
1878-4046
Statut éditorial
Publié
Date de publication
2014-05
Volume
21
Numéro
5
Première page
675
Dernière page/numéro d’article
684
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Résumé
To provide an updated evidence-based review of the literature on the role of fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) or PET/computed tomography (PET/CT) in patients with sarcoidosis.
A comprehensive literature search of PubMed/MEDLINE, Scopus, and Embase databases was conducted to find relevant published articles on FDG-PET or PET/CT in patients with sarcoidosis. Only those studies that satisfied all the following criteria were included: (1) FDG-PET or PET/CT performed in patients with histologically confirmed sarcoidosis, (2) sample size of at least 10 patients, and (3) whole-body PET studies performed. Information was collected concerning basic study, patient characteristics, and technical aspects. The main findings of the articles included have been described.
Reviewing titles and abstracts, 21 articles were selected. The role of FDG-PET or PET/CT was analyzed in assessing disease extent and activity and in treatment response evaluation. Comparison with other tracers had also been investigated. Recent studies evaluated the influence of these methods in the clinical management and their role as predictive tools in patients with sarcoidosis.
FDG-PET and PET/CT seem to be useful in staging, evaluating disease activity, and monitoring treatment response in patients with sarcoidosis. PET appears to have higher diagnostic accuracy compared to Gallium-67-citrate scintigraphy. Conversely, there is not enough evidence about the use of other PET tracers in patients with sarcoidosis. FDG-PET and PET/CT seem to have a role as predictive tools and may influence the clinical management in patients with sarcoidosis, but more studies are needed in this regard.
Sujets

Evidence-Based Medici...

Fluorodeoxyglucose F1...

Humans

Image Enhancement/met...

Multimodal Imaging/me...

Positron-Emission Tom...

Radiopharmaceuticals

Reproducibility of Re...

Sarcoidosis/diagnosis...

Sensitivity and Speci...

Tomography, X-Ray Com...

Positron emission tom...

fluorodeoxyglucose

sarcoidosis

PID Serval
serval:BIB_016DC9095A70
DOI
10.1016/j.acra.2014.01.008
PMID
24703482
WOS
000334559200017
Permalien
https://iris.unil.ch/handle/iris/43544
Date de création
2017-08-20T17:22:24.836Z
Date de création dans IRIS
2025-05-20T14:14:41Z
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