Titre
Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Cevey-Macherel, M.
Auteure/Auteur
Galetto-Lacour, A.
Auteure/Auteur
Gervaix, A.
Auteure/Auteur
Siegrist, C.A.
Auteure/Auteur
Bille, J.
Auteure/Auteur
Bescher-Ninet, B.
Auteure/Auteur
Kaiser, L.
Auteure/Auteur
Krahenbuhl, J.D.
Auteure/Auteur
Gehri, M.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1432-1076[electronic]
Statut éditorial
Publié
Date de publication
2009
Volume
168
Numéro
12
Première page
1429
Dernière page/numéro d’article
1436
Langue
anglais
Résumé
Community-acquired pneumonia (CAP) is a major cause of death in developing countries and of morbidity in developed countries. The objective of the study was to define the causative agents among children hospitalized for CAP defined by WHO guidelines and to correlate etiology with clinical severity and surrogate markers. Investigations included an extensive etiological workup. A potential causative agent was detected in 86% of the 99 enrolled patients, with evidence of bacterial (53%), viral (67%), and mixed (33%) infections. Streptococcus pneumoniae was accounted for in 46% of CAP. Dehydration was the only clinical sign associated with bacterial pneumonia. CRP and PCT were significantly higher in bacterial infections. Increasing the number of diagnostic tests identifies potential causes of CAP in up to 86% of children, indicating a high prevalence of viruses and frequent co-infections. The high proportion of pneumococcal infections re-emphasizes the importance of pneumococcal immunization.
PID Serval
serval:BIB_B897BFDE2F2C
PMID
Open Access
Oui
Date de création
2009-11-24T15:25:31.010Z
Date de création dans IRIS
2025-05-21T01:21:18Z
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Nom
REF.pdf
Version du manuscrit
published
Taille
190.86 KB
Format
Adobe PDF
PID Serval
serval:BIB_B897BFDE2F2C.P001
URN
urn:nbn:ch:serval-BIB_B897BFDE2F2C5
Somme de contrôle
(MD5):79b78c023dfb50c27d8ebd6cc9818962