Titre
Assessing Pseudomonas aeruginosa Persister/antibiotic tolerant cells.
Type
chapitre
Institution
Externe
Auteur(s)
Hazan, R.
Auteure/Auteur
Maura, D.
Auteure/Auteur
Que, Y.A.
Auteure/Auteur
Rahme, L.G.
Auteure/Auteur
Liens vers les personnes
Maison dāĆ©dition
Springer
Titre du livre ou confƩrence/colloque
Methods in Molecular Biology
Statut Ć©ditorial
PubliƩ
Date de publication
2014
Volume
1149
Chapitre
54
PremiĆØre page
699
DerniĆØre page/numĆ©ro dāarticle
707
Peer-reviewed
Oui
Langue
anglais
RƩsumƩ
Bacterial persistence, which is observed in a broad range of microbial species, is the capacity of a bacterial cell subpopulation called "persisters" to tolerate exposure to normally lethal concentrations of bactericidal antibiotics. This ability, which is not due to antibiotic-resistant mutants, has been implicated in antibiotic treatment failures and may account for latent, chronic, and relapsing infections. Antibiotic tolerant/Persister (AT/P) cells have been notoriously difficult to study due to their low frequency and transient nature. This chapter describes the main methods used to isolate and study Pseudomonas aeruginosa AT/P cells and discusses new technologies that may ease research of P. aeruginosa persisters in the near future.
PID Serval
serval:BIB_03FD913C231C
PMID
Date de crƩation
2014-10-28T08:08:16.807Z
Date de crƩation dans IRIS
2025-05-20T16:08:44Z