Titre

Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial.

Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Wald, R.
Auteure/Auteur
Gaudry, S.
Auteure/Auteur
da Costa, B.R.
Auteure/Auteur
Adhikari, NKJ
Auteure/Auteur
Bellomo, R.
Auteure/Auteur
Du, B.
Auteure/Auteur
Gallagher, M.P.
Auteure/Auteur
Hoste, E.A.
Auteure/Auteur
Lamontagne, F.
Auteure/Auteur
Joannidis, M.
Auteure/Auteur
Liu, K.D.
Auteure/Auteur
McAuley, D.F.
Auteure/Auteur
McGuinness, S.P.
Auteure/Auteur
Nichol, A.D.
Auteure/Auteur
Ostermann, M.
Auteure/Auteur
Palevsky, P.M.
Auteure/Auteur
Qiu, H.
Auteure/Auteur
Pettilä, V.
Auteure/Auteur
Schneider, A.G.
Auteure/Auteur
Smith, O.M.
Auteure/Auteur
Vaara, S.T.
Auteure/Auteur
Weir, M.
Auteure/Auteur
Dreyfuss, D.
Auteure/Auteur
Bagshaw, S.M.
Auteure/Auteur
Contributrices/contributeurs
Bagshaw, S.M.
Wald, R.
Adhikari, NKJ
Bellomo, R.
Dreyfuss, D.
Du, B.
Gallagher, M.P.
Gaudry, S.
Hoste, E.A.
Lamontagne, F.
Joannidis, M.
Liu, K.D.
McAuley, D.F.
McGuinness, S.P.
Nichol, A.D.
Ostermann, M.
Palevsky, P.M.
Qiu, H.
Pettilä, V.
Schneider, A.G.
Smith, O.M.
Vaara, S.T.
Weir, M.
Bellomo, R.
Eastwood, G.M.
Peck, L.
Young, H.
Kruger, P.
Laurie, G.
Saylor, E.
Meyer, J.
Venz, E.
Wetzig, K.
French, C.
McGain, F.
Mulder, J.
Fennessy, G.
Koottayi, S.
Bates, S.
Towns, M.
Morgan, R.
Tippett, A.
Udy, A.
Mason, C.
Licari, E.
Gantner, D.
McClure, J.
Nichol, A.
McCracken, P.
Board, J.
Martin, E.
Vallance, S.
Young, M.
Vladic, C.
McGloughlin, S.
Gattas, D.
Buhr, H.
Coles, J.
Hutch, D.
Wun, J.
Cole, L.
Whitehead, C.
Lowrey, J.
Masters, K.
Gresham, R.
Campbell, V.
Gutierrez, D.
Brailsford, J.
Forbes, L.
Murray, L.
Maguire, T.
NiChonghaile, M.
Orford, N.
Bone, A.
Elderkin, T.
Salerno, T.
Chimunda, T.
Fletcher, J.
Broadfield, E.
Porwal, S.
Knott, C.
Boschert, C.
Smith, J.
Richardson, A.
Hill, D.
Duke, G.
Oziemski, P.
Cegarra, S.
Chan, P.
Welsh, D.
Hunter, S.
Roodenburg, O.
Dyett, J.
Kokotsis, N.
Moser, M.
Yang, X
Padayachee, L.
Vetro, J.
Gangopadhyay, H.
Kaufman, M.
Ghosh, A.
Said, S.
Patel, A.
Bihari, S.
Matheson, E.
Jin, X.
Shrestha, T.
Schwartz, K.
Gallagher, M.P.
Cross, R.
Cheung, W.
Wong, H.
Kol, M.
Shah, A.
Wang, A.Y.
Endre, Z.
Bradford, C.
Janin, P.
Finfer, S.
Diel, N.
Gatward, J.
Hammond, N.
Delaney, A.
Bass, F.
Yarad, E.
Buscher, H.
Reynolds, C.
Baker, N.
Joannidis, M.
Bellmann, R.
Peer, A.
Hasslacher, J.
Koglberger, P.
Klein, S.
Zotter, K.
Brandtner, A.
Finkenstedt, A.
Ditlbacher, A.
Hartig, F.
Fries, D.
Bachler, M.
Schenk, B.
Wagner, M.
Eller, P.
Staudinger, T.
Tiller, E.
Schellongowski, P.
Bojic, A.
Hoste, E.A.
Bracke, S.
De Crop, L.
Vermeiren, D.
Thome, F.
Chiella, B.
Fendt, L.
Antunes, V.
Lafrance, J.P.
Lamontagne, F.
D'Aragon, F.
St-Arnaud, C.
Mayette, M.
Carbonnaeu, É.
Marchand, J.
Masse, M.H.
Ladouceur, M.
Turgeon, A.F.
Lauzier, F.
Bellemare, D.
Francoeur, C.L.
LeBlanc, G.
Guilbault, G.
Grenier, S.
Cloutier, E.
Boivin, A.
Delisle-Thibault, C.
Giannakouros, P.
Costerousse, O.
Cailhier, J.F.
Carrier, F.M.
Ghamraoui, A.
Lebrasseur, M.
Benettaib, F.
Salamé, M.
Boumahni, D.
Sia, Y.T.
Naud, J.F.
Roy, I.
Stelfox, H.T.
Ruddell, S.
Manns, B.J.
Duggan, S.
Carney, D.
Barchard, J.
Whitlock, R.P.
Belley-Cote, E.
Savija, N.
Sabev, A.
Campbell, T.
Creary, T.
Devereaux, K.
Brodutch, S.
Rigatto, C.
Paunovic, B.
Mooney, O.
Glybina, A.
Harasemiw, O.
Di Nella, M.
Harmon, J.
Mehta, N.
Lakatos, L.
Haslam, N.
Lellouche, F.
Simon, M.
Tung, Y.
Lizotte, P.
Bourchard, P.A.
Rochwerg, B.
Karachi, T.
Millen, T.
Muscedere, J.
Maslove, D.
Boyd, J.G.
Sibley, S.
Drover, J.
Hunt, M.
Georgescu, I.
Wax, R.
Lenga, I.
Sridhar, K.
Steele, A.
Fusco, K.
Ghate, T.
Tolibas, M.
Robinson, H.
Weir, M.A.
Taneja, R.
Ball, I.M.
Garg, A.
Campbell, E.
Ovsenek, A.
Bagshaw, S.M.
van Diepen, S.
Baig, N.
Magder, S.
Yao, H.
Alam, A.
Campisi, J.
MacIntyre, E.
Rokosh, E.
Scherr, K.
Lapinsky, S.
Mehta, S.
Shah, S.
Niven, D.J.
Stelfox, H.T.
Ruddell, S.
Russell, M.
Jim, K.
Brown, G.
Oxtoby, K.
Hall, A.
Benoit, L.
Sokolowski, C.
Prasad, B.
Rao, J.
Giebel, S.
Kutsogiannis, D.J.
Thompson, P.
Thompson, T.
Cirone, R.
Kavikondala, K.
Soth, M.
Clarke, F.
Takaoka, A.
Wald, R.
Mazer, D.
Burns, K.
Friedrich, J.
Klein, D.
Sandhu, G.
Santos, M.
Khalid, I.
Hodder, J.
Dodek, P.
Ayas, N.
Alcuaz, V.
Suen, G.
Rewa, O.
Singh, G.
Norris, S.
Gibson, N.
Arias, C.
Shami, A.
Pelletier, C.
Adhikari, NKJ
Zahirieh, A.
Amaral, A.
Marinoff, N.
Kaur, N.
Perez, A.
Wang, J.
Haljan, G.
Condin, C.
McIntyre, L.
Gomes, B.
Porteous, R.
Watpool, I.
Hiremath, S.
Clark, E.
Herridge, M.S.
Backhouse, F.
Wilcox, M.E.
Walczak, K.
Ki, V.
Sharman, A.
Romano, M.
Bagshaw, S.M.
Gibney, RTN
Romanovsky, A.S.
Rewa, O.
McCoshen, L.
Baig, N.
Wood, G.
Ovakim, D.
Auld, F.
Carney, G.
Duan, M.
Ji, X.
Guo, D.
Qi, Z.
Lin, J.
Zhang, M.
Dong, L.
Liu, J.
Liu, P.
Zhi, D.
Bai, G.
Qiu, Y.
Yang, Z.
Bai, J.
Liu, Z.
Zhuang, H.
Wang, H.
Li, J.
Zhao, M.
Zhou, X.
Shi, X.
Ye, B.
Liu, M.
Wu, J.
Fu, Y.
Long, D.
Pan, Y.
Wang, J.
Mei, H.
Zhang, S.
Wen, M.
Yang, E.
Mu, S.
Li, J.
Hu, T.
Qin, B.
Li, M.
Wang, C.
Dong, X.
Wang, K.
Wang, H.
Yang, J.
Du, B.
Wang, C.
Wang, D.
Li, N.
Yu, Z.
Xu, S.
Yao, L.
Hou, G.
Liu, Z.
Lu, L.
Lian, Y.
Wang, C.
Zhang, J.
Ding, R.
Qi, G.
Wang, Q.
Wang, P.
Meng, Z.
Chen, M.
Hu, X.
He, X.
Zhao, S.
Hang, L.
Li, R.
Qin, S.
Lu, K.
Dun, S.
Liu, C.
Zhou, Q.
Chen, Z.
Mei, J.
Zhang, M.
Xu, H.
Lin, J.
Shi, Q.
Fu, L.
Zeng, Q.
Ma, H.
Yan, J.
Gao, L.
Liu, H.
Zhang, L.
Li, H.
He, X.
Fan, J.
Guo, L.
Liu, Y.
Wang, X.
Sun, J.
Liu, Z.
Yang, J.
Ding, L.
Sheng, L.
Liu, X.
Yan, J.
Wang, Q.
Wang, Y.
Zhao, D.
Zhao, S.
Hu, C.
Li, J.
Deng, F.
Qui, H.
Yang, Y.
Mo, M.
Pan, C.
Wu, C.
Huang, Y.
Huang, L.
Liu, A.
Pettilä, V.
Vaara, S.T.
Korhonen, A.M.
Törnblom, S.
Sutinen, S.
Pettilä, L.
Heinonen, J.
Lappi, E.
Suhonen, T.
Karlsson, S.
Hoppu, S.
Jalkanen, V.
Kuitunen, A.
Levoranta, M.
Långsjö, J.
Ristimäki, S.
Malila, K.
Wootten, A.
Varila, S.
Järvisalo, M.J.
Inkinen, O.
Kentala, S.
Leivo, K.
Haltia, P.
Dreyfuss, D.
Ricard, J.D.
Messika, J.
Tiagarajah, A.
Emery, M.
Dechanet, A.
Gernez, C.
Roux, D.
Martin-Lefevre, L.
Fiancette, M.
Vinatier, I.
Lacherade, J.C.
Colin, G.
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Azais, M.A.
Yehia, A.
Pouplet, C.
Lagarrigue, M.H.
Seguin, A.
Crosby, L.
Maizel, J.
Titeca-Beauport, D.
Combes, A.
Nieszkowska, A.
Masi, P.
Demoule, A.
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Marque, S.
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Andreu, P.
Dargent, A.
Large, A.
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Barbier, F.
Bretagnol, A.
Kamel, T.
Mathonnet, A.
Muller, G.
Skarzynski, M.
Rossi, J.
Pradet, A.
Dos Santos, S.
Guery, A.
Muller, L.
Felix, L.
Bohé, J.
Thiéry, G.
Aissaoui, N.
Vimpere, D.
Commeureuc, M.
Diehl, J.L.
Guerot, E.
Liangos, O.
Wittig, M.
Zarbock, A.
Küllmar, M.
van Waegeningh, T.
Rosenow, N.
Nichol, A.D.
Brickell, K.
Doran, P.
Murray, P.T.
Landoni, G.
Lembo, R.
Zangrillo, A.
Monti, G.
Tozzi, M.
Marzaroli, M.
Lombardi, G.
Paternoster, G.
Vitiello, M.
McGuinness, S.
Parke, R.
Butler, M.
Gilder, E.
Cowdrey, K.A.
Wallace, S.
Hallion, J.
Woolett, M.
Neal, P.
Duffy, K.
Long, S.
McArthur, C.
Simmonds, C.
Chen, Y.
McConnochie, R.
Newby, L.
Knight, D.
Henderson, S.
Mehrtens, J.
Morgan, S.
Morris, A.
Vander Hayden, K.
Burke, T.
Bailey, M.
Freebairn, R.
Chadwick, L.
Park, P.
Rolls, C.
Thomas, L.
Buehner, U.
Williams, E.
Albrett, J.
Kirkham, S.
Jackson, C.
Browne, T.
Goodson, J.
Jackson, D.
Houghton, J.
Callender, O.
Higson, V.
Keet, O.
Dominy, C.
Young, P.
Hunt, A.
Judd, H.
Lawrence, C.
Olatunji, S.
Robertson, Y.
Latimer-Bell, C.
Hendry, D.
Mckay-Vucago, A.
Beehre, N.
Eden, X
Lesona, X
Navarra, L.
Robinson, C.
Jang, R.
Junge, A.
Lambert, B.
Schneider, A.G.
Thibault, M.
Eckert, P.
Kissling, S.
Polychronopoulos, E.
Poli, E.
Altarelli, M.
Schnorf, M.
Mallaird, S.A.
Heidegger, C.
Perret, A.
Montillier, P.
Sangla, F.
Neils, S.
De Watteville, A.
Phull, M.K.
George, A.
Hussain, N.
Pogreban, T.
Lobaz, S.
Daniels, A.
Cunningham, M.
Kerr, D.
Nicholson, A.
Shanmugasundaram, P.
Abrams, J.
Manso, K.
Hambrook, G.
McKerrow, E.
Salva, J.
Foulkes, S.
Wise, M.
Morgan, M.
Brooks, J.
Cole, J.
Davies, T.M.
Hill, H.
Thomas, E.
Vizcaychipi, M.
Baharlo, B.
Carungcong, J.
Costa, P.
Martins, L.
Kapoor, R.
Hazelton, T.
Moon, A.
Musselwhite, J.
Shelley, B.
McCall, P.
Ostermann, M.
Arbane, G.
Bociek, A.
Marotti, M.
Lim, R.
Campos, S.
Novellas, N.G.
Cennamo, A.
Slack, A.
Wyncoll, D.
Camporota, L.
Sparkes, S.
Tilley, R.
Rattray, A.
Moreland, G.
Duffy, J.
McGonigal, E.
Hopkins, P.
Finney, C.
Smith, J.
Noble, H.
Watson, H.
Harris, C.L.
Clarey, E.
Corcoran, E.
Beck, J.
Howcroft, C.
Youngs, N.
Wilby, E.
Ogg, B.
Wolverson, A.
Lee, S.
Butler, S.
Okubanjo, M.
Hindle, J.
Welters, I.
Williams, K.
Johnson, E.
Patrick-Heselton, J.
Shaw, D.
Waugh, V.
Stewart, R.
Mwaura, E.
Wren, L.
Mew, L.
Sutherland, S.B.
Adderley, J.
Ruddy, J.
Harkins, M.
Kaye, C.
Scott, T.
Mitchell, W.
Anderson, F.
Willox, F.
Jagannathan, V.
Clark, M.
Purv, S.
Sharman, A.
Meredith, M.
Ryan, L.
Conner, L.
Peters, C.
Harvey, D.
Roshdy, A.
Collins, A.
Sim, M.
Henderson, S.
Chee, N.
Pitts, S.
Bowman, K.
Dilawershah, M.
Vamplew, L.
Howe, E.
Rogers, P.
Hernandez, C.
Prendergast, C.
Benton, J.
Rosenberg, A.
Forni, L.G.
Grant, A.
Carvelli, P.
Raithatha, A.
Bird, S.
Richardson, M.
Needham, M.
Hirst, C.
Ball, J.
Leaver, S.
Howlett, L.
Delgado, C.C.
Farnell-Ward, S.
Farrah, H.
Gray, G.
Joseph, G.
Robinson, F.
Tridente, A.
Harrop, C.
Shuker, K.
McLaughlan, D.
Ramsey, J.
Meehan, S.
Rose, B.O.
Reece-Anthony, R.
Gurung, B.
Whitehouse, T.
Snelson, C.
Veenith, T.
Johnston, A.
Cooper, L.
Carrera, R.
Ellis, K.
Fellows, E.
Harkett, S.
Bergin, C.
Spruce, E.
Despy, L.
Goundry, S.
Dooley, N.
Mason, T.
Clark, A.
Dignam, G.
Ward, G.
Attwood, B.
Parsons, P.
Mason, S.
Margarson, M.
Lord, J.
McGlone, P.
Hodgson, L.E.
Chadbourn, I.
Gomez, R.
Margalef, J.
Pretorius, R.
Hamshere, A.
Carter, J.
Cahill, H.
Grainger, L.
Howard, K.
Forshaw, G.
Guy, Z.
Kashani, K.B.
Albright, R.C.
Amsbaugh, A.
Stoltenberg, A.
Niven, A.S.
Lynch, M.
O'Mara, A.
Naeem, S.
Sharif, S.
Goulart, J.M.
Lynch, M.
O'Mara, A.
Naeem, S.
Sharif, S.
Goulart, J.M.
Tolwani, A.
Lyas, C.
Latta, L.
Bihorac, A.
Hashemighouchani, H.
Efron, P.
Ruppert, M.
Cupka, J.
Kiley, S.
Carson, J.
White, P.
Omalay, G.
Brown, S.
Velez, L.
zMarceron, A.
Neyra, J.A.
Aycinena, J.C.
Elias, M.
Ortiz-Soriano, V.M.
Hauschild, C.
Dorfman, R.
Groupes de travail
STARRT-AKI Investigators
Liens vers les personnes
Liens vers les unités
ISSN
1432-1238
Statut éditorial
Publié
Date de publication
2023-11
Volume
49
Numéro
11
Première page
1305
Dernière page/numéro d’article
1316
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Clinical Trial ; Journal Article
Publication Status: ppublish
Résumé
There is controversy regarding the optimal renal-replacement therapy (RRT) modality for critically ill patients with acute kidney injury (AKI).
We conducted a secondary analysis of the STandard versus Accelerated Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial to compare outcomes among patients who initiated RRT with either continuous renal replacement therapy (CRRT) or intermittent hemodialysis (IHD). We generated a propensity score for the likelihood of receiving CRRT and used inverse probability of treatment with overlap-weighting to address baseline inter-group differences. The primary outcome was a composite of death or RRT dependence at 90-days after randomization.
We identified 1590 trial participants who initially received CRRT and 606 who initially received IHD. The composite outcome of death or RRT dependence at 90-days occurred in 823 (51.8%) patients who commenced CRRT and 329 (54.3%) patients who commenced IHD (unadjusted odds ratio (OR) 0.90; 95% confidence interval (CI) 0.75-1.09). After balancing baseline characteristics with overlap weighting, initial receipt of CRRT was associated with a lower risk of death or RRT dependence at 90-days compared with initial receipt of IHD (OR 0.81; 95% CI 0.66-0.99). This association was predominantly driven by a lower risk of RRT dependence at 90-days (OR 0.61; 95% CI 0.39-0.94).
In critically ill patients with severe AKI, initiation of CRRT, as compared to IHD, was associated with a significant reduction in the composite outcome of death or RRT dependence at 90-days.
Sujets

Humans

Acute Kidney Injury/t...

Continuous Renal Repl...

Critical Illness/ther...

Renal Dialysis

Renal Replacement The...

Acute kidney injury

Continuous

Intermittent hemodial...

Modality

Mortality

Randomized trial

Renal-replacement the...

PID Serval
serval:BIB_8C33F301F2E2
DOI
PMID
WOS
Permalien
Date de création
2023-10-13T08:02:38.991Z
Date de création dans IRIS
2025-05-21T02:43:00Z