Titre
Effect of menstrual cycle phase on physiological responses in healthy women at rest and during submaximal exercise at high altitude.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Tagliapietra, G.
Auteure/Auteur
Citherlet, T.
Auteure/Auteur
Raberin, A.
Auteure/Auteur
Bourdillon, N.
Auteure/Auteur
Krumm, B.
Auteure/Auteur
Narang, B.J.
Auteure/Auteur
Giardini, G.
Auteure/Auteur
Pialoux, V.
Auteure/Auteur
Debevec, T.
Auteure/Auteur
Millet, G.P.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
2045-2322
Statut éditorial
Publié
Date de publication
2024-11-13
Volume
14
Numéro
1
Première page
27793
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Résumé
As more women engage in high-altitude activities, understanding how ovarian hormone fluctuations affect their cardiorespiratory system is essential for optimizing acclimatization to these environments. This study investigates the effects of menstrual cycle (MC) phases on physiological responses at rest, during and after submaximal exercise, at high-altitude (barometric pressure 509 ± 6 mmHg; partial pressure of inspired oxygen 96 ± 1 mmHg; ambient temperature 21 ± 2 °C and relative humidity 27 ± 4%) in 16 eumenorrheic women. Gas exchange, hemodynamic responses, heart rate variability and heart rate recovery (HRR) were monitored at low altitude, and then at 3375 m on the Mont Blanc (following nocturnal exposure) during both the early-follicular (EF) and mid-luteal (ML) phases. Significant differences were observed between low and high-altitude in ventilation, heart rate and cardiac output. Resting ventilation (15.2 ± 1.9 vs. 13.2 ± 2.5 L.min <sup>-1</sup> ; p = 0.039) and tidal volume (812 ± 217 vs. 713 ± 190 mL; p = 0.027) were higher during EF than ML at high-altitude. These differences between EF and ML were no longer evident during exercise, with comparable responses in oxygen uptake kinetics, cycling efficiency and HRR. The MC had negligible effects on physiological responses to high-altitude. An individualized approach, tailored to each woman's specific responses to hypoxia across the MC, may be more beneficial in optimizing high-altitude sojourns than general guidelines.
Sujets
PID Serval
serval:BIB_CA7705430B19
PMID
Open Access
Oui
Date de création
2024-11-18T11:07:01.099Z
Date de création dans IRIS
2025-05-21T04:36:33Z
Fichier(s)![Vignette d'image]()
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Nom
475. Tagliapietra SciRep24 MenstrualCycle Exercise Altitude.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
2.16 MB
Format
Adobe PDF
PID Serval
serval:BIB_CA7705430B19.P001
URN
urn:nbn:ch:serval-BIB_CA7705430B193
Somme de contrôle
(MD5):a3dcdaaf2dac7a02b2f60e17e31c2cdd