Titre
Neuroactive metabolites modulated by the gut microbiota in honey bees.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Cabirol, A.
Auteure/Auteur
Moriano-Gutierrez, S.
Auteure/Auteur
Engel, P.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1365-2958
Statut éditorial
Publié
Date de publication
2024-09
Volume
122
Numéro
3
Première page
284
Dernière page/numéro d’article
293
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Review ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
Honey bees have emerged as a new model to study the gut-brain axis, as they exhibit complex social behaviors and cognitive abilities, while experiments with gnotobiotic bees have revealed that their gut microbiota alters both brain and behavioral phenotypes. Furthermore, while honey bee brain functions supporting a broad range of behaviors have been intensively studied for over 50 years, the gut microbiota of bees has been experimentally characterized only recently. Here, we combined six published datasets from metabolomic analyses to provide an overview of the neuroactive metabolites whose abundance in the gut, hemolymph and brain varies in presence of the gut microbiota. Such metabolites may either be produced by gut bacteria, released from the pollen grains during their decomposition by bacteria, or produced by other organs in response to different bacterial products. We describe the current state of knowledge regarding the impact of such metabolites on brain function and behavior and provide further hypotheses to explore in this emerging field of research.
PID Serval
serval:BIB_3ADF7D01186D
PMID
Open Access
Oui
Date de création
2023-09-25T15:49:30.393Z
Date de création dans IRIS
2025-05-20T20:18:36Z
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Nom
37718573.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by-nc/4.0
Taille
957.02 KB
Format
Adobe PDF
PID Serval
serval:BIB_3ADF7D01186D.P001
URN
urn:nbn:ch:serval-BIB_3ADF7D01186D2
Somme de contrôle
(MD5):5332784a6de04d83fdc107256df82fcb