Titre
The EuroSIDA study: Regional differences in the HIV-1 epidemic and treatment response to antiretroviral therapy among HIV-infected patients across Europe--a review of published results.
Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Podlekareva, D.
Auteure/Auteur
Bannister, W.
Auteure/Auteur
Mocroft, A.
Auteure/Auteur
Abrosimova, L.
Auteure/Auteur
Karpov, I.
Auteure/Auteur
Lundgren, J.D.
Auteure/Auteur
Kirk, O.
Auteure/Auteur
Contributrices/contributeurs
Losso, M.
Duran, A.
Vetter, N.
Karpov, I.
Vassilenko, A.
Mitsura, VM.
Suetnov, O.
Clumeck, N.
De Wit, S.
Poll, B.
Colebunders, R.
Kostov, K.
Begovac, J.
Machala, L.
Rozsypal, H.
Sedlácek, D.
Nielsen, J.
Lundgren, J.
Benfield, T.
Kirk, O.
Gerstoft, J.
Katzenstein, T.
Hansen, AB.
Skinhøj, P.
Pedersen, C.
Oestergaard, L.
Zilmer, K.
Ristola, M.
Katlama, C.
Viard, JP.
Girard, PM.
Livrozet, JM.
Vanhems, P.
Pradier, C.
Dabis, F.
Neau, D.
Rockstroh, J.
Schmidt, R.
van Lunzen, J.
Degen, O.
Stellbrink, HJ.
Staszewski, S.
Goethe, JW.
Bogner, J.
Fätkenheuer, G.
Kosmidis, J.
Gargalianos, P.
Xylomenos, G.
Perdios, J.
Panos, G.
Filandras, A.
Karabatsaki, E.
Sambattakou, H.
Banhegyi, D.
Mulcahy, F.
Yust, I.
Turner, D.
Burke, M.
Pollack, S.
Hassoun, G.
Maayan, S.
Chiesi, A.
Esposito, R.
Mazeu, I.
Mussini, C.
Arici, C.
Pristera, R.
Mazzotta, F.
Gabbuti, A.
Vullo, V.
Lichtner, M.
Chirianni, A.
Montesarchio, E.
Gargiulo, M.
Antonucci, G.
Iacomi, F.
Narciso, P.
Vlassi, C.
Zaccarelli, M.
Lazzarin, A.
Finazzi, R.
Galli, M.
Ridolfo, A.
d'Arminio, A.
Rozentale, B.
Aldins, P.
Chaplinskas, S.
Hemmer, R.
Staub, T.
Reiss, P.
Bruun, J.
Maeland, A.
Ormaasen, V.
Knysz, B.
Horban, A.
Prokopowicz, D.
Wiercinska-Drapalo, A.
Boron-Kaczmarska, A.
Pynka, M.
Beniowski, M.
Mularska, E.
Trocha, H.
Antunes, F.
Valadas, E.
Mansinho, K.
Maltez, F.
Duiculescu, D.
Babes, V.
Rakhmanova, A.
Vinogradova, E.
Buzunova, S.
Jevtovic, D.
Mokrás, M.
Staneková, D.
González-Lahoz, J.
Soriano, V.
Martin-Carbonero, L.
Labarga, P.
Clotet, B.
Jou, A.
Conejero, J.
Tural, C.
Gatell, JM.
Miró, JM.
Domingo, P.
Gutierrez, M.
Mateo, G.
Sambeat, MA.
Karlsson, A.
Persson, PO.
Flamholc, L.
Ledergerber, B.
Weber, R.
Francioli, P.
Cavassini, M.
Hirschel, B.
Boffi, E.
Furrer, H.
Battegay, M.
Elzi, L.
Kravchenko, E.
Chentsova, N.
Barton, S.
Johnson, AM.
Mercey, D.
Phillips, A.
Johnson, MA.
Mocroft, A.
Murphy, M.
Weber, J.
Scullard, G.
Fisher, M.
Brettle, R.
Clotet, B.
Antunes, F.
Clotet, B.
Duiculescu, D.
Gatell, J.
Gazzard, B.
Horban, A.
Karlsson, A.
Katlama, C.
Ledergerber, B.
D'Arminio Montforte, A.
Phillips, A.
Rakhmanova, A.
Reiss, P.
Rockstroh, J.
Lundgren, J.
Kirk, O.
Mocroft, A.
Friis-Møller, N.
Cozzi-Lepri, A.
Bannister, W.
Ellefson, M.
Borch, A.
Podlekareva, D.
Kjaer, J.
Peters, L.
Reekie, J.
Groupes de travail
EuroSIDA Study Group
Liens vers les personnes
Liens vers les unités
ISSN
1210-7778
Statut éditorial
Publié
Date de publication
2008-09
Volume
16
Numéro
3
Première page
99
Dernière page/numéro d’article
105
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
EuroSIDA is a pan-European observational study that follows 14,265 HIV-infected patients from 31 European countries, Israel and Argentina, of which 2,560 are patients from eastern Europe (EE). The study group has performed several analyses addressing regional differences in the HIV-epidemic across Europe, where all countries were divided into five regions: south, west central, north, east central Europe and EE. Significant regional differences in patients' characteristics and pattern of AIDS diagnoses were documented. More patients from EE were diagnosed with tuberculosis compared to other regions. Significantly fewer HIV-infected patients in EE, who fulfilled the criteria for starting combination antiretroviral therapy (cART), actually received cART as compared with other regions of Europe. Those, receiving cART in EE had a lower initial virologic response rate irrespectively of the regimen used, although it has improved within years. Besides, treatment failure was more common in this region. Thus, improvements in the clinical management of HIV patients in EE are urgently needed. Strategies include creating scientific collaborations for HIV clinicians as well as teaching clinicians about the most advanced HIV management at clinically oriented courses held in eastern Europe.
PID Serval
serval:BIB_DAE6CB1BCF34
PMID
Date de création
2009-03-05T15:44:47.764Z
Date de création dans IRIS
2025-05-21T05:54:42Z