Titre
A randomised controlled trial of the pectoral nerves-2 (PECS-2) block for radical mastectomy.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Auteur(s)
Al Ja'bari, A.
Auteure/Auteur
Robertson, M.
Auteure/Auteur
El-Boghdadly, K.
Auteure/Auteur
Albrecht, E.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1365-2044
Statut éditorial
Publié
Date de publication
2019-10
Volume
74
Numéro
10
Première page
1277
Dernière page/numéro d’article
1281
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Randomized Controlled Trial
Publication Status: ppublish
Publication Status: ppublish
Résumé
We randomly allocated 50 women scheduled for radical mastectomy to pectoral nerves-2 (PECS-2) block (n = 25) or no block (n = 25), 20 and 22 of whom we analysed for the primary outcome of a cumulative 24-h postoperative morphine dose. We gave intra-operative sufentanil, magnesium, dexamethasone and droperidol. Participants received regular postoperative paracetamol, ibuprofen and patient-controlled intravenous morphine. Pectoral nerves-2 block reduced mean (SD) cumulative 24 h postoperative morphine dose from 9.7 (8.9) mg to 5.0 (5.4) mg and 48 h morphine dose from 12.8 (12.5) mg to 6.0 (6.5) mg, p = 0.04 for both. The mean (SD) pain scores 24 h and 48 h after surgery were similar with or without block: 0.8 (1.4) vs. 1.2 (1.9), p = 0.39; and 0.2 (0.4) vs. 0.9 (1.8), p = 0.09, respectively. Rates of postoperative nausea, vomiting and pruritus were unaffected. Rates of chronic pain at six postoperative months were 2/19 and 2/18 after block and no block, respectively, p = 0.95.
Sujets
PID Serval
serval:BIB_8B4FBCFCD10B
PMID
Date de création
2019-07-21T15:10:19.382Z
Date de création dans IRIS
2025-05-20T22:05:13Z