Titre
Therapie der CED bei Steroidversagen : Immunsuppressiva oder Biologika? [Therapy of steroid resistant inflammatory bowel disease Immunomodulators or biologicals?]
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Manz, M.
Auteure/Auteur
Schoepfer, A.M.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0174-2442
Statut éditorial
Publié
Date de publication
2014-12
Volume
36
Numéro
6
Première page
433
Dernière page/numéro d’article
438
Langue
allemand
Résumé
Although systemic corticosteroids are often successfully applied for induction of clinical response and remission of inflammatory bowel disease (IBD) patients presenting with a flare, a proportion of these treated patients present with a primary non-response to steroids, resistance or steroid dependence. Long-term therapy with corticosteroids for treatment of IBD should be avoided given the high frequency of adverse treatment effects. This article highlights the indications for the use of immunomodulators (e.g. azathioprine, 6-mercaptopurine and methotrexate), drugs directed against tumor necrosis factor (anti-TNF) as well as calcineurin inhibitors (e.g. cyclosporine and tacrolimus).
PID Serval
serval:BIB_A3D3F7F372AF
Date de création
2021-07-28T08:36:58.664Z
Date de création dans IRIS
2025-05-20T21:11:09Z
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Nom
146.pdf
Version du manuscrit
published
Taille
375.94 KB
Format
Adobe PDF
PID Serval
serval:BIB_A3D3F7F372AF.P001
URN
urn:nbn:ch:serval-BIB_A3D3F7F372AF8
Somme de contrôle
(MD5):3bc1c1885860f0c009afeecf5d4fe46c