Titre
Assessing clinical outcome of transplant patients by means of the INTERMED
Type
abstract de conférence/colloque
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Série
Journal of Psychosomatic Research
Auteur(s)
Ludwig, G.
Auteure/Auteur
Berney, Sylvie
Auteure/Auteur
Suchar, G.
Auteure/Auteur
Ostacoli, L.
Auteure/Auteur
Lobo, E.
Auteure/Auteur
Jonge Peter, de
Auteure/Auteur
Stiefel, Friedrich
Auteure/Auteur
Söllner, Wolfgang
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISBN
0022-3999
Statut éditorial
Publié
Date de publication
2006
Volume
60
Première page
661
Peer-reviewed
Oui
Langue
anglais
Notes
SAPHIRID:61569
Résumé
Aim: The objective of this ongoing multicentric study is to evaluate if the INTERMED (IM), a screening instrument to assess case complexity, identifies patients at risk for unfavourable postoperative development.
Methods: So far, 217 kidney (KTX) and liver (LTX) transplant patients were evaluated preoperatively and 70 of them at 12 months post transplant. Biopsychosocial profiles were assessed using the IM. Quality of life [Short Form 36 (SF-36)] and depressive symptomatology (HADS) were measured before transplant (TX) and 1 year after transplantation. Correlations between the IM scores pre transplant and SF-36 and HADS scores at follow-up were studied after controlling for baseline measures.
Results: At baseline, LTX scored higher on the depression subscale, the sum-score of the HADS (P b.001, Mliver/kidney depression 7.81/6.08, Mliver/kidney sum-score 15.1/12.3) and lower on the SF-36 physical-health scale (Mliver/kidney 36.0/42.3). For the whole sample, we could not state a significant relationship between the IM sum-score before TX and SF-36 and HADS measures after TX, but we found a negative correlation between the IM psychological domain and the SF-36 subscale vitality (r=_0.37) and mental health scale (r=_0.50). For KTX, a negative correlation was found between the IM sum-score 1, the biological 2, and the psychological 3 domain and the SF-36 scale physical functioning (r1=_0.56, r2=_0.46, r3=_0.57). For LTX, a negative correlation (r=_0.38) emerged for the IM psychological domain and the SF-36 subscale vitality.
Discussion: This preliminary analysis demonstrates a certain predictive quality of the IM, indicating an association of higher IM scores with an increased risk for poor health-related quality of life after TX. We plan to present an elaborated analysis of our findings at the conference.
Methods: So far, 217 kidney (KTX) and liver (LTX) transplant patients were evaluated preoperatively and 70 of them at 12 months post transplant. Biopsychosocial profiles were assessed using the IM. Quality of life [Short Form 36 (SF-36)] and depressive symptomatology (HADS) were measured before transplant (TX) and 1 year after transplantation. Correlations between the IM scores pre transplant and SF-36 and HADS scores at follow-up were studied after controlling for baseline measures.
Results: At baseline, LTX scored higher on the depression subscale, the sum-score of the HADS (P b.001, Mliver/kidney depression 7.81/6.08, Mliver/kidney sum-score 15.1/12.3) and lower on the SF-36 physical-health scale (Mliver/kidney 36.0/42.3). For the whole sample, we could not state a significant relationship between the IM sum-score before TX and SF-36 and HADS measures after TX, but we found a negative correlation between the IM psychological domain and the SF-36 subscale vitality (r=_0.37) and mental health scale (r=_0.50). For KTX, a negative correlation was found between the IM sum-score 1, the biological 2, and the psychological 3 domain and the SF-36 scale physical functioning (r1=_0.56, r2=_0.46, r3=_0.57). For LTX, a negative correlation (r=_0.38) emerged for the IM psychological domain and the SF-36 subscale vitality.
Discussion: This preliminary analysis demonstrates a certain predictive quality of the IM, indicating an association of higher IM scores with an increased risk for poor health-related quality of life after TX. We plan to present an elaborated analysis of our findings at the conference.
PID Serval
serval:BIB_C61317493233
Date de création
2008-03-10T09:28:02.710Z
Date de création dans IRIS
2025-05-20T23:16:04Z