Titre
A statistical methodology for the comparison of blue gel pen inks analyzed by laser desorption/ionization mass spectrometry
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Weyermann, C.
Auteure/Auteur
Bucher, L.
Auteure/Auteur
Majcherczyk, P.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1355-0306
Statut éditorial
Publié
Date de publication
2011
Volume
51
Numéro
3
Première page
122
Dernière page/numéro d’article
130
Peer-reviewed
Oui
Langue
anglais
Notes
http://dx.doi.org/10.1016/j.scijus.2010.10.008
Résumé
A statistical methodology for the objective comparison of LDI-MS mass spectra of blue gel pen inks was evaluated. Thirty-three blue gel pen inks previously studied by RAMAN were analyzed directly on the paper using both positive and negative mode. The obtained mass spectra were first compared using relative areas of selected peaks using the Pearson correlation coefficient and the Euclidean distance. Intra-variability among results from one ink and inter-variability between results from different inks were compared in order to choose a differentiation threshold minimizing the rate of false negative (i.e. avoiding false differentiation of the inks). This yielded a discriminating power of up to 77% for analysis made in the negative mode. The whole mass spectra were then compared using the same methodology, allowing for a better DP in the negative mode of 92% using the Pearson correlation on standardized data. The positive mode results generally yielded a lower differential power (DP) than the negative mode due to a higher intra-variability compared to the inter-variability in the mass spectra of the ink samples.
PID Serval
serval:BIB_8E07357CF840
Open Access
Oui
Date de création
2010-12-08T10:12:59.279Z
Date de création dans IRIS
2025-05-20T23:42:36Z
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Nom
BIB_8E07357CF840.P001.pdf
Version du manuscrit
preprint
Taille
346.79 KB
Format
Adobe PDF
PID Serval
serval:BIB_8E07357CF840.P001
URN
urn:nbn:ch:serval-BIB_8E07357CF8408
Somme de contrôle
(MD5):8af55bed08fcc867ecd075ffe28e1c73