Titre
Obese but Fit: The Benefits of Fitness on Cognition in Obese Older Adults.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Boidin, M.
Auteure/Auteur
Handfield, N.
Auteure/Auteur
Ribeiro, PAB
Auteure/Auteur
Desjardins-Crépeau, L.
Auteure/Auteur
Gagnon, C.
Auteure/Auteur
Lapierre, G.
Auteure/Auteur
Gremeaux, V.
Auteure/Auteur
Lalongé, J.
Auteure/Auteur
Nigam, A.
Auteure/Auteur
Juneau, M.
Auteure/Auteur
Gayda, M.
Auteure/Auteur
Bherer, L.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1916-7075
Statut éditorial
Publié
Date de publication
2020-11
Volume
36
Numéro
11
Première page
1747
Dernière page/numéro d’article
1753
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
Obesity is associated with an accelerated cognitive decline. Aerobic fitness has a protective effect on cognition in older adults, but no study has investigated this effect in obese individuals. The present study aimed to 1) compare cognitive function in lower-fit (LoFit) and higher-fit (HiFit) obese individuals compared with nonobese individuals, and 2) examine the association between exercise variables (including hemodynamic variables) and cognitive function in obese individuals.
Fifty-four obese and 16 nonobese individuals performed a maximal cardiopulmonary exercise test (with gas exchange analysis and noninvasive hemodynamic measurement) and cognitive tests assessing short-term and working memory, processing speed, executive function, and long-term verbal memory. Obese individuals were divided into 2 groups according to their median aerobic fitness divided by lean body mass to form a group of LoFit obese (n = 27) and a group of HiFit obese (n = 27) individuals.
A total of 14 nonobese individuals and 49 obese individuals were included in the final analysis (HiFit: n = 26, LoFit: n = 23). Compared with LoFit obese, HiFit obese participants had greater performances in executive function (P = 0.002) and short-term memory (P = 0.02). Nonobese and HiFit obese participants showed equivalent performances in all domains of cognition. In obese individuals, aerobic fitness was the only independent predictor for short-term memory (R <sup>2</sup> = 0.24; P < 0.001), working memory (R <sup>2</sup> = 0.16; P = 0.02), processing speed (R <sup>2</sup> = 0.22; P = 0.01), and executive function (R <sup>2</sup> = 0.49; P = 0.003), but not for long-term verbal memory (R <sup>2</sup> = 0.15; P = 0.26).
HiFit obese individuals showed greater short-term memory and executive function performances compared with LoFit obese individuals, suggesting that aerobic fitness could help preserve cognitive function despite the presence of obesity.
Fifty-four obese and 16 nonobese individuals performed a maximal cardiopulmonary exercise test (with gas exchange analysis and noninvasive hemodynamic measurement) and cognitive tests assessing short-term and working memory, processing speed, executive function, and long-term verbal memory. Obese individuals were divided into 2 groups according to their median aerobic fitness divided by lean body mass to form a group of LoFit obese (n = 27) and a group of HiFit obese (n = 27) individuals.
A total of 14 nonobese individuals and 49 obese individuals were included in the final analysis (HiFit: n = 26, LoFit: n = 23). Compared with LoFit obese, HiFit obese participants had greater performances in executive function (P = 0.002) and short-term memory (P = 0.02). Nonobese and HiFit obese participants showed equivalent performances in all domains of cognition. In obese individuals, aerobic fitness was the only independent predictor for short-term memory (R <sup>2</sup> = 0.24; P < 0.001), working memory (R <sup>2</sup> = 0.16; P = 0.02), processing speed (R <sup>2</sup> = 0.22; P = 0.01), and executive function (R <sup>2</sup> = 0.49; P = 0.003), but not for long-term verbal memory (R <sup>2</sup> = 0.15; P = 0.26).
HiFit obese individuals showed greater short-term memory and executive function performances compared with LoFit obese individuals, suggesting that aerobic fitness could help preserve cognitive function despite the presence of obesity.
PID Serval
serval:BIB_DAAE69D71592
PMID
Date de création
2020-07-08T10:57:00.091Z
Date de création dans IRIS
2025-05-21T00:58:32Z
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Nom
2020_Boidin_CJCardiol_Obese but Fit.pdf
Version du manuscrit
preprint
Taille
381.22 KB
Format
Adobe PDF
PID Serval
serval:BIB_DAAE69D71592.P001
Somme de contrôle
(MD5):8349bec8896794b2589c3a178c4e86b1