Titre
Le microbiote cutané: le poids lourd sort de l'ombre [The skin microbiota: a colossus steps into the spotlight]
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Di Domizio, J.
Auteure/Auteur
Pagnoni, A.
Auteure/Auteur
Huber, M.
Auteure/Auteur
Hohl, D.
Auteure/Auteur
Gilliet, M.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
2016-03-30
Volume
12
Numéro
512
Première page
660
Dernière page/numéro d’article
664
Peer-reviewed
Oui
Langue
français
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
The skin contains many commensal bacteria. For years, these microbes have been considered to be exploiters of the human host for nutrients. However, recent findings indicates that the skin microbiota is also used by the human host to protect himself against invading pathogens as the commensal bacteria have direct antimicrobial capacity and provide factors required to mount a protective immune responses in the skin. While the healthy skin microbiome functions as guardians of host defense, increased or decreased bacterial composition of the skin microbiome (called dysbiosis) leads to skin inflammation and disease. Here we will review the emerging data on the role of distinct types of dysbiosis in the pathogenesis skin diseases and illustrate how the new understanding of the role of the skin microbiome has implications in the clinical management of skin diseases.
Sujets
PID Serval
serval:BIB_DAFF9A45E42A
PMID
Date de création
2020-07-14T08:06:54.269Z
Date de création dans IRIS
2025-05-21T00:58:58Z
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Nom
RMS_512_660.pdf
Version du manuscrit
published
Taille
3.37 MB
Format
Adobe PDF
PID Serval
serval:BIB_DAFF9A45E42A.P001
Somme de contrôle
(MD5):d19b64d5a64c8449166d3cbebdcba739