Titre
A new method for quantitative ultrasound measurements at multiple skeletal sites: first results of precision and fracture discrimination.
Type
article
Institution
Externe
Périodique
Auteur(s)
Barkmann, R.
Auteure/Auteur
Kantorovich, E.
Auteure/Auteur
Singal, C.
Auteure/Auteur
Hans, D.
Auteure/Auteur
Genant, H.K.
Auteure/Auteur
Heller, M.
Auteure/Auteur
Glüer, C.C.
Auteure/Auteur
Liens vers les personnes
ISSN
1094-6950
Statut éditorial
Publié
Date de publication
2000
Volume
3
Numéro
1
Première page
1
Dernière page/numéro d’article
7
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article
Résumé
We investigated a new multisite quantitative ultrasound device that measures the acoustic velocity in axial transmission mode along the cortex. Using a prototype of the Omnisense (Sunlight Ultrasound Technologies, Rehovot, Israel), we tested the performance of this instrument at four sites of the skeleton: radius, ulna, metacarpal, and phalanx. Intraobserver (interobserver) precision errors ranged from 0.2% to 0.3% (0.3% to 0.7%) for triplicate measurements with repositioning. Fracture discrimination was tested by comparing a group of 34 women who had previously suffered a fracture of the hip, spine, ankle, or forearm to a group of 28 healthy women who had not suffered a fracture. Age-adjusted standardized odds ratios ranged from 1.6 to 4.5. Except for the ulna the sites showed a significant fracture discrimination (p < 0.01). The areas under the receiver operating curves (ROC) curves were from 0.88 to 0.89 for radius, metacarpal, and phalanx. A combination of the results from the three sites showed a significant increase of the ROC area to 0.95 (p < 0. 05). Our results show promising performance of this new device. The ability to measure a large variety of sites and the potential to combine these measurements are promising with regard to optimizing fracture risk assessment.
PID Serval
serval:BIB_952363CEF65D
PMID
Date de création
2009-03-02T11:33:34.843Z
Date de création dans IRIS
2025-05-21T01:13:39Z