Titre
Anemia and chronic kidney disease are associated with poor outcomes in heart failure patients.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
PĂ©riodique
Auteur(s)
Luthi, J.C.
Auteure/Auteur
Flanders, W.D.
Auteure/Auteur
Burnier, M.
Auteure/Auteur
Burnand, B.
Auteure/Auteur
McClellan, W.M.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1471-2369[electronic]
Statut Ă©ditorial
Publié
Date de publication
2006
Volume
7
Première page
3
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: epublish
Résumé
BACKGROUND: Chronic kidney disease (CKD) has been linked to higher heart failure (HF) risk. Anemia is a common consequence of CKD, and recent evidence suggests that anemia is a risk factor for HF. The purpose of this study was to examine among patients with HF, the association between CKD, anemia and inhospital mortality and early readmission. METHODS: We performed a retrospective cohort study in two Swiss university hospitals. Subjects were selected based the presence of ICD-10 HF codes in 1999. We recorded demographic characteristics and risk factors for HF. CKD was defined as a serum creatinine > or = 124 956;mol/L for women and > or = 133 micromol/L for men. The main outcome measures were inhospital mortality and thirty-day readmissions. RESULTS: Among 955 eligible patients hospitalized with heart failure, 23.0% had CKD. Twenty percent and 6.1% of individuals with and without CKD, respectively, died at the hospital (p < 0.0001). Overall, after adjustment for other patient factors, creatinine and hemoglobin were associated with an increased risk of death at the hospital, and hemoglobin was related to early readmission. CONCLUSION: Both CKD and anemia are frequent among older patients with heart failure and are predictors of adverse outcomes, independent of other known risk factors for heart failure.
PID Serval
serval:BIB_89AE09013B1C
PMID
Open Access
Oui
Date de création
2008-03-04T13:58:27.798Z
Date de création dans IRIS
2025-05-21T02:08:52Z
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Nom
BIB_89AE09013B1C.P001.pdf
Version du manuscrit
preprint
Taille
284.32 KB
Format
Adobe PDF
PID Serval
serval:BIB_89AE09013B1C.P001
URN
urn:nbn:ch:serval-BIB_89AE09013B1C4
Somme de contrĂ´le
(MD5):67a31f4368f61885fdddd1e5af0c35bd