Titre
Association Between Traumatic Brain Injury-Related Brain Lesions and Long-term Caregiver Burden.
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Guevara, A.B.
Auteure/Auteur
Demonet, J.F.
Auteure/Auteur
Polejaeva, E.
Auteure/Auteur
Knutson, K.M.
Auteure/Auteur
Wassermann, E.M.
Auteure/Auteur
Grafman, J.
Auteure/Auteur
Krueger, F.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1550-509X
Statut éditorial
Publié
Date de publication
2016
Volume
31
Numéro
2
Première page
E48
Dernière page/numéro d’article
58
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
To investigate the association between traumatic brain injury (TBI)-related brain lesions and long-term caregiver burden in relation to dysexecutive syndrome.
National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.
A total of 256 participants: 105 combat veterans with TBI, 23 healthy control combat veterans (HCv), and 128 caregivers.
Caregiver burden assessed by the Zarit Burden Interview at 40 years postinjury.
Participants with penetrating TBI were compared with HCv on perceived caregiver burden and neuropsychological assessment measures. Data of computed tomographic scans (overlay lesion maps of participants with a penetrating TBI whose caregivers have a significantly high burden) and behavioral statistical analyses were combined to identify brain lesions associated with caregiver burden.
Burden was greater in caregivers of veterans with TBI than in caregivers of HCv. Caregivers of participants with lesions affecting cognitive and behavioral indicators of dysexecutive syndrome (ie, left dorsolateral prefrontal cortex and dorsal anterior cingulate cortex) showed greater long-term burden than caregivers of participants with lesions elsewhere in the brain.
The TBI-related brain lesions have a lasting effect on long-term caregiver burden due to cognitive and behavioral factors associated with dysexecutive syndrome.
National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.
A total of 256 participants: 105 combat veterans with TBI, 23 healthy control combat veterans (HCv), and 128 caregivers.
Caregiver burden assessed by the Zarit Burden Interview at 40 years postinjury.
Participants with penetrating TBI were compared with HCv on perceived caregiver burden and neuropsychological assessment measures. Data of computed tomographic scans (overlay lesion maps of participants with a penetrating TBI whose caregivers have a significantly high burden) and behavioral statistical analyses were combined to identify brain lesions associated with caregiver burden.
Burden was greater in caregivers of veterans with TBI than in caregivers of HCv. Caregivers of participants with lesions affecting cognitive and behavioral indicators of dysexecutive syndrome (ie, left dorsolateral prefrontal cortex and dorsal anterior cingulate cortex) showed greater long-term burden than caregivers of participants with lesions elsewhere in the brain.
The TBI-related brain lesions have a lasting effect on long-term caregiver burden due to cognitive and behavioral factors associated with dysexecutive syndrome.
PID Serval
serval:BIB_C0D4E0E6E8FE
PMID
Date de création
2016-04-26T15:51:01.747Z
Date de création dans IRIS
2025-05-21T02:30:51Z