Titre
Previous thyroid disease and risk of thyroid cancer in Switzerland
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Levi, F.
Auteure/Auteur
Franceschi, S.
Auteure/Auteur
La Vecchia, C.
Auteure/Auteur
Negri, E.
Auteure/Auteur
Gulie, C.
Auteure/Auteur
Duruz, G.
Auteure/Auteur
Scazziga, B.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
0959-8049
Statut éditorial
Publié
Date de publication
1991
Volume
27
Numéro
1
Première page
85
Dernière page/numéro d’article
88
Peer-reviewed
Oui
Langue
anglais
Résumé
A hospital-based case-control study of 86 cases of thyroid cancer and 317 controls was done in the Swiss Canton of Vaud. Patients with thyroid cancer tended to be better educated (odds ratio [OR] 2.1 for greater than or equal to 14 vs. less than or equal to 8 years of education 95% CI 1.1-4.1) and of higher social class than controls. Cases more often had a history of benign thyroid nodules (OR 25.2, 95% CI 7.6-83.6) and non-toxic goitre (OR 5.3, 95% CI 2.5-11.2). Furthermore, patients with thyroid cancer were more likely to have resided in endemic goitre areas (OR 1.7, 95% CI 1.0-3.0) and to have had first-degree relatives affected by benign thyroid disease (OR 3.9, 95% CI 2.1-7.1). Therefore, this study offers quantitative evidence of the association between various thyroid diseases and the risk of thyroid cancer which, despite difficulties in the classification of benign and malignant thyroid diseases, is remarkably consistent in studies from different countries.
PID Serval
serval:BIB_B70391CBF27A
PMID
Date de création
2015-01-08T15:56:59.831Z
Date de création dans IRIS
2025-05-21T02:50:10Z