Titre
When food meets man: the contribution of epigenetics to health.
Type
synthèse (review)
Institution
Externe
Périodique
Auteur(s)
De Fabiani, E.
Auteure/Auteur
Mitro, N.
Auteure/Auteur
Gilardi, F.
Auteure/Auteur
Galmozzi, A.
Auteure/Auteur
Caruso, D.
Auteure/Auteur
Crestani, M.
Auteure/Auteur
Liens vers les personnes
ISSN
2072-6643
Statut éditorial
Publié
Date de publication
2010-05
Volume
2
Numéro
5
Première page
551
Dernière page/numéro d’article
571
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Publication Status: ppublish
Résumé
Post-translational modifications of chromatin contribute to the epigenetic control of gene transcription. The response to food intake and individual nutrients also includes epigenetic events. Bile acids are necessary for lipid digestion and absorption, and more recently have emerged as signaling molecules. Their synthesis is transcriptionally regulated also in relation to the fasted-to-fed cycle, and interestingly, the underlying mechanisms include chromatin remodeling at promoters of key genes involved in their metabolism. Several compounds present in nutrients affect gene transcription through epigenetic mechanisms and recent studies demonstrate that, beyond the well known anti-cancer properties, they beneficially affect energy metabolism.
Sujets
PID Serval
serval:BIB_AC0115928608
PMID
URL éditeur
Open Access
Oui
Date de création
2019-03-21T10:29:33.014Z
Date de création dans IRIS
2025-05-21T03:54:56Z