Titre

Epidermolyse nécrosante suraiguë de Lyell ou toxic epidermal necrolysis [Toxic epidermal necrolysis]

Type
synthèse (review)
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Bigliardi, P.L.
Auteure/Auteur
Raffoul, W.
Auteure/Auteur
Berger, M.M.
Auteure/Auteur
Liens vers les personnes
Liens vers les unités
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
2007-05-02
Volume
3
Numéro
109
Première page
1112
Dernière page/numéro d’article
1114
Peer-reviewed
Oui
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Résumé
The toxic epidermal necrolysis (TEN) is an immunologic reaction in the skin with apoptosis of kératinocytes: most cases are reactions against drugs. The main features of this reaction are a separation of the epidermis and erosions of the mucus membranes, associated with a reduction of the general condition with kidney and liver failure. This leads to problems similar to those observed in severely burned patients. The mortality high of patients with TEN can be reduced, if the responsible drug is immediately withdrawn and if the patient is treated in a specialized burns intensive care unit. The medical treatment to stop the chain reaction of apoptosis is still under discussion. Through a case report, this article will focus on the complexity of the treatment of patients with TEN and will point out the importance of a multidisciplinary approach.
Sujets

Diagnosis, Differenti...

Humans

Male

Middle Aged

Stevens-Johnson Syndr...

Stevens-Johnson Syndr...

Stevens-Johnson Syndr...

PID Serval
serval:BIB_073D8BBA0929
DOI
PMID
Permalien
Date de création
2008-01-21T16:30:36.322Z
Date de création dans IRIS
2025-05-20T14:17:06Z
Fichier(s)
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Nom

RMS_Epidermolyse nécrosante suraiguë de Lyell ou toxic epidermal necrolysis.pdf

Version du manuscrit

published

Licence

https://creativecommons.org/licenses/by-nc-nd/4.0

Taille

329.6 KB

Format

Adobe PDF

PID Serval

serval:BIB_073D8BBA0929.P001

URN

urn:nbn:ch:serval-BIB_073D8BBA09295

Somme de contrôle

(MD5):6c4c4c5853807053bc6e9e919832c72e