Titre
Evolution of impulsivity levels in relation to early cannabis use in violent patients in the early phase of psychosis
Type
article
Institution
UNIL/CHUV/Unisanté + institutions partenaires
Périodique
Auteur(s)
Dan-Glauser, Elise
Auteure/Auteur
Framorando, David
Auteure/Auteur
Solida-Tozzi, Alessandra
Auteure/Auteur
Golay, Philippe
Auteure/Auteur
Gholam, M. Mehdi
Auteure/Auteur
Alameda, Luis
Auteure/Auteur
Conus, Philippe
Auteure/Auteur
Moulin, Valerie
Auteure/Auteur
Liens vers les personnes
ISSN
0033-2917
Statut éditorial
Publié
Date de publication
2023-05
Volume
53
Numéro
7
Première page
3210
Dernière page/numéro d’article
3219
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Prevention of violent behaviors (VB) in the early phase of psychosis (EPP) is a real challenge. Impulsivity was shown to be strongly related to VB, and different evolutions of impulsivity were noticed along treatments. One possible variable involved in the relationship between VB and the evolution of impulsivity is cannabis use (CU). The high prevalence of CU in EPP and its relationship with VB led us to investigate: 1/the impact of CU and 2/the impact of early CU on the evolution of impulsivity levels during a 3-year program, in violent and non-violent EPP patients.
178 non-violent and 62 violent patients (VPs) were followed-up over a 3 year period. Age of onset of CU was assessed at program entry and impulsivity was assessed seven times during the program. The evolution of impulsivity level during the program, as a function of the violent and non-violent groups of patients and CU precocity were analyzed with linear mixed-effects models.
Over the treatment period, impulsivity level did not evolve as a function of the interaction between group and CU (coef. = 0.02, p = 0.425). However, when including precocity of CU, impulsivity was shown to increase significantly only in VPs who start consuming before 15 years of age (coef. = 0.06, p = 0.008).
The precocity of CU in VPs seems to be a key variable of the negative evolution of impulsivity during follow-up and should be closely monitored in EPP patients entering care since they have a higher risk of showing VB.
178 non-violent and 62 violent patients (VPs) were followed-up over a 3 year period. Age of onset of CU was assessed at program entry and impulsivity was assessed seven times during the program. The evolution of impulsivity level during the program, as a function of the violent and non-violent groups of patients and CU precocity were analyzed with linear mixed-effects models.
Over the treatment period, impulsivity level did not evolve as a function of the interaction between group and CU (coef. = 0.02, p = 0.425). However, when including precocity of CU, impulsivity was shown to increase significantly only in VPs who start consuming before 15 years of age (coef. = 0.06, p = 0.008).
The precocity of CU in VPs seems to be a key variable of the negative evolution of impulsivity during follow-up and should be closely monitored in EPP patients entering care since they have a higher risk of showing VB.
PID Serval
serval:BIB_12697C8084DB
PMID
Open Access
Oui
Date de création
2022-02-10T17:35:20.868Z
Date de création dans IRIS
2025-05-20T14:20:23Z
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Nom
evolution-of-impulsivity-levels-in-relation-to-early-cannabis-use-in-violent-patients-in-the-early-phase-of-psychosis.pdf
Version du manuscrit
published
Licence
https://creativecommons.org/licenses/by/4.0
Taille
289.19 KB
Format
Adobe PDF
PID Serval
serval:BIB_12697C8084DB.P001
URN
urn:nbn:ch:serval-BIB_12697C8084DB3
Somme de contrôle
(MD5):f8ca09bcad68e8f0707dc89decd2b2be